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Breast Cancer Nomogram to Predict Additional Positive Non-SLN, without Neoadjuvant Chemotherapy


This software calculates the probablility of finding additional positive non-sentinel lymph nodes in breast cancer patients found to have disease on sentinel lymph node biopsy without completion of neoadjuvant chemotherapy. This nomogram was developed at the University of Texas M. D. Anderson Cancer Center and has been externally validated.

Enter SLN metastasis size as a categorical variable (ITC, micrometastasis or macrometasis).

Choose the histologic type of the tumor. The "Other" category includes mucinous, tubular, papillary and medullary tumors.
Size of the primary tumor, in centimeters, on surgical pathology.
(cm)
Total number of lymph nodes removed, either SLN or non-SLN, during SLN dissection. Enter a number from 1-13.
Total number of SLNs found to contain cancer. Enter a number from 1-6.
Indicate the size of the largest focus of metastasis found in the SLN by pathologic examination, in millimeters. If the exact size is not known, enter the size of the metastasis by category (macrometastasis, micrometastasis, ITC) by clicking on the link above.
(mm)
Indicate whether any extranodal extension was identified in the positive lymph node(s).
Indicate whether tumor cells were present in blood vessels or lymphatic structures.


Reference: E. Mittendorf, J. Boughey, A. Degnim, R. Harrell, R. Bassett, M. Yi, F. Meric-Bernstam, M. Ross, G. Babiera, H. Kuerer, A. Lucci, I. Bedrosian, K. Hunt, R. Hwang. Accepted for presentation at the San Antonio Breast Cancer Symposium, December 2010