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AJCC 6th Edition
Primary Tumor (T)
TX: Primary tumor cannot be assessed
T0: No evidence of primary tumor
Tis: Carcinoma in situ (DCIS, LCIS, Paget´s disease with no invasive tumor)
Invasive tumor measurement in greatest dimension
T1mic: Microinvasive <= 0.1 cm
T1a: >0.1 cm to 0.5 cm
T1b: >0.5 cm to 1 cm
T1c: >1 cm to 2 cm
T2: >2 cm to 5 cm
T3: >5 cm
Tumor of any size with direct extension to
T4a: Extension to chest wall, not including pectoralis muscle
T4b: Edema/peau d´orange or ulceration of the skin of the breast, or satellite skin nodules confined to the same breast
T4c: Both T4a and T4b
T4d: Inflammatory carcinoma
Regional (Ipsilateral) Lymph Nodes (N)
pNX: Cannot be assessed (e.g. previously removed, or not removed for pathologic study)
pN0: No regional lymph node metastasis histologically, no additional examination for ITC
Axillary lymph node metastasis (including axillary fat deposit and intramammary nodes)
Micrometastasis ( >0.2 mm to 2.0 mm)
1 to 3 axillary lymph nodes
4 to 9 axillary lymph nodes (at least 1 tumor deposit > 2.0 mm)
>= 10 axillary lymph nodes (at least 1 tumor deposit > 2.0 mm)
Distant Metastasis (M)
MX: Distant metastasis cannot be assessed
M0: No distant metastasis
M1: Distant metastasis