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Decoding Breast Cancer Predisposition Genes

Decoding Breast Cancer Predisposition Genes

The Division of Cancer Prevention and Population Sciences, Cancer Prevention & Control Grand Rounds

presents Dr.  Fergus J. Couch from the Mayo Clinic on Friday, March 3, 2017.

Date: 3/3/17, 12pm to 1pm
Time: 3/3/17, 12pm to 1pm
Location: Cancer Prevention Building, Floor 8, Rooms 7-8
Format: Grand Rounds
CME: 1
Speaker: Dr. Fergus J. Couch
Speaker Bio: Fergus J. Couch, Ph.D. is the Zbigniew and Anna M. Scheller Professor in Medical Research and Chair of the Division of Experimental Pathology and Laboratory Medicine within the Department of Laboratory Medicine and Pathology at the Mayo Clinic. He holds joint appointments in the Departments of Health Sciences Research and Biochemistry and Molecular Biology. Dr. Couch works on the genetics of breast cancer, with over 400 publications relating to the discovery and clinical characterization of inherited genetic variants in cancer susceptibility genes. Dr. Couch is the principal investigator of the Mayo Clinic Breast Cancer Registry and is a founder and a member of the coordinating committee of CIMBA (the consortium of investigators of modifiers of BRCA1/2) that is focused on identifying genetic modifiers of breast cancer risk in the BRCA1 carrier population. Similarly, he is the principal investigator of the Triple Negative Breast Cancer Consortium (TNBCC), aimed at understanding the genetic etiology of triple negative breast cancer, and is a long-term contributor to the international Breast Cancer Association Consortium (BCAC). Dr. Couch is a co-founder of the Evidence-based Network for the Interpretation of Germline Mutant Alleles (ENIGMA) consortium that is focused on establishing the clinical relevance of variants of uncertain significance (VUS) in Cancer Predisposition Genes using in silico prediction models, family-based studies, and functional assays. He serves on expert panels for classification of variants in BRCA1 and BRCA2 for the ClinVar and the BRCA Challenge BRCA exchange websites and is a member of the steering committee for the Prospective Registry Of Multi-Plex Testing (PROMPT), a direct to patient follow up study of individuals with inherited variants in predisposition genes. Finally, Dr. Couch is a founding member and participant in COMPLEXO, a consortium of investigators aiming to identify additional breast cancer predisposition genes.
Contact: Jennifer Castillo - (832) 750-1629 -