Skip to Content

MD Anderson Events

Energy Balance Journal Club - Animal Models and Physical Activity

Energy Balance Journal Club - Animal Models and Physical Activity


Animal Models and Physical Activity
Facilitated by Rosie Schmandt, PhD & Zobeida Cruz-Monserrate, PhD
Friday, October 11, 2013
12:00 – 1:00pm
FCT3.4166 Room 2 & Room 7
Lunch provided to the first 20 attendees
Articles include:
·         Phillip B, Roland CL, Daniluk J, Liu Y, et al. A High-Fat Diet Activates Oncogenic Kras and COX2 to Induce Development of Pancreatic Ductal Adenocarcinoma in Mice.
·         Bradley RL, Jeon JY, Liu FF, Maratos-Flier E. Voluntary exercise improves insulin sensitivity and adipose tissue inflammation in diet-induced obese mice.
·         Basterfield L, Reul JM, Mathers JC. Impact of Physical Activity on Intestinal Cancer Development in Mice.


The Center for Energy Balance in Cancer Prevention and Survivorship’s monthly trans-disciplinary journal club aims to bring researchers from multiple disciplines together to examine different energy balance-related topics.
Center for Energy Balance in Cancer Prevention and Survivorship is directed by Karen Basen-Engquist, Ph.D., M.P.H

Date: 10/11/13, 12pm to 1pm
Time: 10/11/13, 12pm to 1pm
Location: Pickens Academic Tower, Floor 3, Room 2 (FCT3.4166)
Format: All Employee Meeting
Speaker: Dr. Rosie Schmandt & Dr. Zobeida Cruz-Monserrate
Speaker Bio: Dr. Rosie Schmandt’s current research interests include the determination of the molecular mechanisms underlying the detrimental effects of stress and obesity on both ovarian and endometrial tumor growth, and how behavioral changes, including diet and exercise, can reverse these effects. In collaboration with Dr, Karen Lu and Dr. Samuel Mok her lab-based studies aim to characterize the direct mechanisms by which diet and exercise modulate the growth of tumor cells and prevent cancer recurrence in mouse models of gynecologic tumors. Zobeida Cruz-Monserrate Ph.D., is an instructor in the Department of Cancer Biology. She is a Cancer Cell Biologist specializing in understanding the mechanisms involved in the development of pancreatic ductal adenocarcinoma (PDAC) in order to develop measures for its prevention and early detection. In this regard, she has developed an animal model of high-fat diet induced PDAC and has identified compounds that prevent cancer in this model. Dr. Cruz-Monserrate has also utilized the enzyme Cathepsin E which is specifically expressed early in PDAC to develop novel therapeutic and diagnostic (theranostic) probes. These probes with proper development will be useful in the clinic toward the goal of early detection that will save lives. Her dedication to making a difference in patients drives the translational aspects of her work.
Sponsor: Center for Energy Balance in Cancer Prevention and Survivorship
Contact: Nazim Ali - (713) 792-2431 -
  EB Jo Club 10.11.13 Flier.pdf (PDF, 218 KB)