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New Frontiers in Therapeutic Agents: Successes in Drugging the Undruggable

New Frontiers in Therapeutic Agents: Successes in Drugging the Undruggable



Kevin Dalby, Ph.D., The University of Texas at Austin
Philip Jones, Ph.D., The University of Texas MD Anderson Cancer Center

Significant advances in drugging difficult targets have been made in academic and industrial research centers, and numerous novel therapies are moving forward into clinic trials across different disease areas. The goal of this symposium is to provide illustrations of how these clinical agents have been developed and progressed into clinical trials. Examples will demonstrate how novel targets have been evaluated for druggability, how different approaches have been adopted to identify novel chemical matter, and steps leading to maturation of leads into novel therapeutic agents.

Keynote Speakers:


Additional invited speakers include:


Kevin Burgess, Ph.D., Texas A&M University

Kurt Deshayes, Ph.D., Genentech

Christopher Dinsmore, Ph.D., Forma Therapeutics

Scott Gilbertson, Ph.D., University of Houston

John MacMillan, University of Texas Southwestern

John McMurray, Ph.D., MD Anderson Cancer Center

Tamas Oravez, Ph.D. Lexicon Pharmaceuticals

Dafyd Owen, Ph.D., Pfizer

Jun Qi, Ph.D., Dana-Farber Cancer Institute

Ami Shah, Ph.D., GlaxoSmithKline

Robert Sims, Ph.D., Constellation Pharmaceuticals

Yongcheng Song, Ph.D., Baylor College of Medicine

Nicholas Terrett, Ph.D., Ensemble Therapeutics Corporation

Sharad Verma, Ph.D., GlaxoSmithKline

Sean Xie, Ph.D., University of Pittsburgh


“RAS: The Elephant in the Room of Cancer Therapy”
     -Garth Powis, Ph.D., Sanford Burnham Medical Research Institute
“Total Synthesis of Natural and Designed Molecules of Biological and Medical Importance”
     -K.C. Nicolaou, Ph.D., Rice University

Date: 4/16/14 to 4/17/14
Time: 4/16/14, 8:30am to 4/17/14, 12pm
Location: BioScience Research Collaborative - 6500 Main Street, Houston, Texas 77030
Format: Research Program
Contact: Shannon Hurst - (713) 792-8543 -
  TxSACT - AGENDA.pdf (PDF, 120 KB)
  TxSACT - April 16 - 17, 2014.pdf (PDF, 202 KB)
  TxSACT - MAP.pdf (PDF, 987 KB)

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