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MD Anderson Events

Pancreas Cancer Seminar Series

Pancreas Cancer Seminar Series

You are cordially invited to attend The Pancreas Cancer Seminar Series presentation by Dr. Eduardo Vilar Sanchez Assistant Professor, Assistant Professor, Department of Clinical Cancer Prevention, Division of OVP, Cancer Prevention and Population Sciences- titled "Genomic Analysis of Colorectal Polyps in Hereditary High-Risk CRC Populations: Opportunities for Prevention".

The Pancreas Cancer Seminar Series meeting (PCSS) is a bi-weekly series where a multi-disciplinary group meets to exchange ideas and research about pancreatic cancer. Invited speakers come both from within the core group of pancreatic cancer researchers, as well as those that might contribute meaningfully to the ongoing team science efforts in pancreatic cancer on campus.

Date: 2/24/17, 10am to 11am
Time: 2/24/17, 10am to 11am
Location: Pickens Tower FCT3.5001
Format: Seminar/Conference
CME: 0
Facilitator: Anirban Maitra, MBBS
Speaker: Eduardo Vilar- Sancez
Speaker Bio: My research group in MD Anderson is focused in the understanding of the carcinogenesis of the colorectum and in the development of targeted therapies to halt the development and progression of premalignant polyps, as well as colorectal tumors. In order to accomplish this overarching goal, we focused in the study of patients diagnosed with genetic syndromes predisposing to the development of polyps and colorectal cancer [mainly Familial Adenomatous Polyposis (FAP) and Lynch Syndrome]. We have several clinical studies that prospectively collect normal mucosa, polyps, tumor samples and germline from patients diagnosed with FAP and Lynch Syndrome currently treated in MD Anderson. These samples are essential for our research projects. We also maintain several mouse colonies that mimic the phenotype of patients with polyposis (APC/Min and APC1638) and Lynch syndrome (MSH2VilCre mice), as well as other models to study the biology of stem cells of the colonic crypt (Lgr5 mice). These mouse models are essential for cross-species comparisons. At the present time we are performing large scale sequencing of polyps and normal mucosa samples using next-generation sequencing technologies to describe the genomic and transcriptomic landscape of these lesions in both human and mouse samples. These studies are the foundation to propose targeted chemoprevention studies in FAP and Lynch syndrome.
Sponsor: Gastrointestinal Medical Oncology / Sheikh Ahmed Center for Pancreatic Research
Contact: Matonia Figgers - (713) 792-5032 - msfiggers@mdanderson.org