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“The Personalized GMR (Gene Master Regulator) Approach of Thyroid Cancer Gene Therapy”

“The Personalized GMR (Gene Master Regulator) Approach of Thyroid Cancer Gene Therapy”

 Talk by Dumitru Andrei Iacobas, PhD; Associate Professor of Pathology; Director of Systems Biology Core; New York Medical College

 

Synopsis

We prove that cancer nodules and surrounding normal tissue are governed by distinct Gene Master Regulators (GMR) and that smart manipulation of the GMR expression selectively destroys cancer cells. The method relies on an original mathematical algorithm that establishes the gene hierarchy from the transcriptomic profiles of tumor biopsies based on their Gene Commanding Height, a composite measure of gene expression control and coordination.

 

Method illustrated in https://doi.org/10.18632/oncotarget.23417ethod illustrated in 

 

Coffee and snacks will be served.

Date: 1/26/18, 11am to 12pm
Time: 1/26/18, 11am to 12pm
Location: 4SCR1.1110
Format: Seminar/Conference
Speaker: Dumitru Andrei Iacobas, Ph.D.
Speaker Bio: Associate Professor of Pathology Director of Systems Biology Core New York Medical College
Contact: Roxanna Anaya - (713) 794-4851 - ranaya@mdanderson.org
Attachments:
  Dumitru Iacobas 1.26.18.pdf (PDF, 45 KB)