MD Anderson Events

John H. Blaffer lecture series

Gerard I. Evan, Ph.D.

Professor, Department of Pathology
School of Medicine, University of California, San Francisco
San Francisco, CA  


Topic:  Targeting tumor suppressor pathways to treat cancer

Date: 12/8/09, 4pm to 5pm
Time: 12/8/09, 4pm to 5pm
Location: Onstead Auditorium, Basic Science Research Building, Floor 3, near Elevator J, (S3.8012)
Directions: Onstead Auditorium is accessible from the Main MDACC Bldg. via the 3rd/4th floor Tan Zone skybridges and the front entrance to BSRB on 6767 Bertner
Format: Lecture
Facilitator: Andreas Bergmann, Ph.D.
Speaker: Gerard I. Evan, Ph.D.
Speaker Bio: Making and Breaking Tumors Our laboratory is interested in the molecular processes that underlie tumorigenesis, tumor progression and tumor maintenance. Cancers appear very different from the normal tissues from which they are presumably derived, and this has engendered the widely held contemporary view that cancers are the protracted end result of a bewildering complexity of molecular lesions that between them drive the formation of the equally complex neoplastic phenotype. However, appearances can be deceiving. We know that many oncogenes are highly pleiotropic "master" switches that modulate a wide variety of mechanistically diverse processes. Consequently, the apparent complexity of cancers may be instructed by a relatively simple, and hence therapeutically tractable, set of molecular lesions. Our overarching aim is to establish what such molecular lesions might be, what effects they have on specific cell types, alone and in combination, and how critical such lesions are not only to drive tumor formation but also to maintain an established tumor.
Sponsor: Department of Genetics
Contact: karen clayton - (713) 834-6317 - kclayton@mdanderson.org

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