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DTSTART:20061101T020000
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UID:1369467885152.mdanderson.org
ORGANIZER;CN=Teresa Gonzales:MAILTO:teresa.gonzales@mdanderson.org
DTSTAMP:20130525T024445
DTSTART;TZID=Central Standard Time:20121107T110000
DTEND;TZID=Central Standard Time:20121107T120000
SUMMARY:The Department of and Bioinformatics and Computational Biology and Distinguished Guest Lecture Series
LOCATION:FCT2.4142 Room B
DESCRIPTION:\nRafael A. Irizarry, Ph.D. \nProfessor, \nBiostatistics \nJohns Hopkins University \nBump hunting in the Cancer Epigenome \nEpigenetics is the study of nonsequence-based changes, such as DNA methylation, heritable during cell division. I will start the talk with a short tutorial on epigenetics and DNA methylation. I will describe new challenges for statisticians related to the existing field of bump hunting. I will describe the important role modern statistical techniques play in finding regions of the genome that are consistently different between disease and normal groups using both microarray and next-generation sequencing data. I will also describe the batch effect and how we deal with it. Finally, I will present some interesting Biological results related to development and cancer.\n\nLocation   : FCT2.4142 Room B\nFormat     : Lecture\nFacilitator: Roel Verhaak\nSpeaker    : Rafael Irizarry\nContact    : Teresa Gonzales - 30299 - teresa.gonzales@mdanderson.org\n\nEvent URL  : http://www3.mdanderson.org/calendar/event/The_Department_of_and_Bioinformatics_and_Computational_Biology_and_Distinguished_Guest_Lecture_Series_18251.html
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