Gary L. Rosner, Sc.D.

Professor of Biostatistics

The University of Texas M. D. Anderson Cancer Center

Some recent publications in peer-reviewed journals:

• Rizzieri DA, Bass AJ, Rosner GL, Gockerman JP, DeCastro CM, Petros WP, Adams DJ, Laughlin MJ, Davis P, Foster T, Jacobson R, Hurwitz H, Moore JO. Phase I evaluation of prolonged-infusion gemcitabine with mitoxantrone for relapsed or refractory acute leukemia. Journal of Clinical Oncology 2002; 20(3):674-679.

• Stroud J, Mueller P, Rosner G. Stimulation-based methods for optimal sampling times in population PK/PD studies. Applied Statistics 2001; 50:345-359.

• Braun RD, Lanzen JL, Turnage JA, Rosner G, Dewhirst MW. Effects of the interaction between carbogen and nicotinamide on R3230 Ac tumor blood flow in Fischer 344 rats. Radiation Research 2001; 155:724-733.

• Müller P, Rosner GL, Inoue LYT, Dewhirst MW. A Bayesian model for detecting acute change in nonlinear profiles. Journal of the American Statistical Association 2001; 96:1215-1222.

• Snyder SA, Lanzen JL, Braun RD, Rosner GL, Secomb TW, Biaglow J, Brizel DM, Dewhirst MW. Simultaneous administration of glucose and hyperoxic gas achieves greater improvement in tumor oxygenation than hyperoxic gas alone. International Journal of Radiation Oncology, Biology, Physics 2001; 51:494-506.

• Maguire PD, Samulski TV, Prosnitz LR, Jones EL, Rosner GL, Powers B, Layfield LW, Brizel DM, Scully SP, Harrelson JM, Dewhirst MW. A phase II trial testing the thermal dose parameter CEM43 degrees T90 as a predictor of response in soft tissue sarcomas treated with pre-operative thermoradiotherapy. International Journal of Hyperthermia 2001; 17(4):283-290.

• Gandhi V, Plunkett W, Weller S, Du M, Ayres M, Rodriguez CO Jr, Ramakrishna P, Rosner GL, Hodge JP, O'Brien S, Keating MJ. Evaluation of the combination of nelarabine and fludarabine in leukemias: clinical response, pharmacokinetics, and pharmacodynamics in leukemia cells. Journal of Clinical Oncology 2001; 19(8):2142-2152.

• Thrall DE, Rosner GL, Azuma C, LaRue SM, Case BC, Samulski T, Dewhirst MW. Using units of CEM 43˚C T90, local hyperthermia thermal dose can be delivered as prescribed. International Journal of Hyperthermia 2000; 16(5):415-428.

• Meyer RE, Braun RD, Rosner GL, Dewhirst MW. Local 42° hyperthermia improves vascular conductance of the R3230Ac rat mammary adenocarcinoma during sodium nitroprusside Infusion. Radiation Research 2000; 154:196-201.

• Matteucci ML, Anyarambhatla G, Rosner G, Azuma C, Fisher PE, Dewhirst MW, Needham D, Thrall DE. Hyperthermia increases accumulation of technetium-99m-labeled liposomes in feline sarcomas. Clinical Cancer Research 2000; 6:3748-3755.

• Venook AP, Egorin MJ, Rosner GL, Hollis D, Mani S, Hawkins M, Byrd J, Hohl R, Budman D, Meropol NJ, Ratain MJ. A phase I and pharmacokinetic trial of gemcitabine in patients with hepatic or renal dysfunction: Cancer and Leukemia Group B 9565. Journal of Clinical Oncology 2000; 18:2780-2787.

• Anscher MS, Lee C, Hurwitz H, Tyler D, Prosnitz LR, Jowell P, Rosner G, Samulski T, Dewhirst MW. A pilot study of preoperative continuous infusion 5-fluorouracil, external microwave hyperthermia, and external beam radiotherapy for treatment of locally advanced, unresectable, or recurrent rectal cancer. International Journal of Radiation Oncology, Biology, Physics 2000; 47:719-724.

• Dunn TJ, Braun RD, Rhemus WE, Rosner GL, Secomb TW, Tozer GJ, Chaplin DJ, Dewhirst MW. The effect of hyperoxic and hypercarbic gases on tumour blood flow. British Journal of Cancer 1999; 80:117-126.

• Prosnitz LR, Maguire P, Anderson JM, Scully SP, Harrelson JM, Jones EL, Dewhirst M, Samulski TV, Powers BE, Rosner GL, Dodge RK, Layfield L, Clough R, Brizel DM. The treatment of high-grade soft tissue sarcomas with preoperative thermoradiotherapy. International Journal of Radiation Oncology, Biology, and Physics 1999; 45: 941-949.