Kenneth R. Hess, Ph.D.

Associate Professor of Biostatistics

The University of Texas M. D. Anderson Cancer Center

 

 

Some recent publications:

 

2002

  • Fuller GN, Hess KR, Rhee CH, Yung WK, Sawaya RA, Bruner JM, Zhang W. Molecular classification of human diffuse gliomas by multidimensional scaling analysis of gene expression profiles parallels morphology-based classification, correlates with survival, and reveals clinically-relevant novel glioma subsets. Brain Pathology 2002; 12(1):108-116.

 

  • Groves MD, Puduvalli VK, Hess KR, Jaeckle KA, Peterson P, Alfred Yung WK, Levin VA. Phase II Trial of Temozolomide Plus the Matrix Metalloproteinase Inhibitor, Marimastat, in Recurrent and Progressive Glioblastoma Multiforme. Journal of Clinical Oncology 2002; 20(5):1383-1388.

 

  • Herrera CA, Xu L, Bucana CD, Silva el VG, Hess KR, Gershenson DM, Fidler IJ. Expression of metastasis-related genes in human epithelial ovarian tumors. International Journal of Oncology 2002; 20(1):5-13.

 

  • Robins HI, Chang SM, Prados MD, Yung WK, Hess KR, Schiff D, Greenberg H, Fink K, Nicolas K, Kuhn JG, Cloughesy T, Junck L, Mehta M.  A phase II trial of thymidine and carboplatin for recurrent malignant glioma:  A North American brain tumor consortium study. Neuro-Oncology 2002; 4:109-114.

  • Shmulevich I, Hunt D, El-Neggar A, Taylor E, Ramdas L, Laborde P, Hess KR, Pollock R, Zhang W.  Tumor specific gene expression profiles in human leiomyosarcoma. Cancer 2002; 94(7):2069-2075. 

 

2001

 

  • Baggerly KA, Coombes KR, Hess KR, Stivers DN, Abruzzo LV, Zhang W. Identifying differentially expressed genes in cDNA microarray experiments. Journal of Computational Biology 2001; 8(6):639-659.

 

  • Breslin TM, Hess KR, Harbison DB, Jean ME, Cleary KR, Dackiw AP, Wolff RA, Abbruzzese JL, Janjan NA, Crane CH, Vauthey JN, Lee JE, Pisters PW, Evans DB. Neoadjuvant chemoradiotherapy for adenocarcinoma of the pancreas: treatment variables and survival duration. Annals of Surgical Oncology 2001; 8(2):123-132.

 

  • Gutman H, Hess KR, Kokotsakis JA, Ross MI, Guinee VF, Balch CM. Surgery for abdominal metastases of cutaneous melanoma. World Journal of Surgery 2001; 25(6):750-758.

 

  • Hess KR, Abbruzzese JL. Matrix metalloproteinase inhibition of pancreatic cancer: matching mechanism of action to clinical trial design (Letter). Journal of Clinical Oncology 2001; 19(15):3445-3446.

 

  • Hess KR, Fuller GN, Rhee CH, Zhang W. Statistical pattern analysis of gene expression profiles for glioblastoma tissues and cell lines. International Journal of Molecular Medicine 2001; 8(2):183-188.

 

  • Hess KR, Zhang W, Baggerly KA, Stivers DN, Coombes KR. Microarrays: handling the deluge of data and extracting reliable information. Trends in Biotechnology 2001; 19(11):463-468.

 

  • Hill LR, Hess KR, Stephens LC, Price RE, Gray KN. Correlation of kidney weight and volume and selected skeletal parameters to sex in the adult rhesus monkey (Macaca mulatta). Journal of Medical Primatology 2001; 30(1):56-60.

 

  • Kozuch P, Hoff PM, Hess KR, Adams J, Newman RA, Lee F, Pazdur R.  Phase I bioequivalency study of MitoExtra and mitomycin C in patients with solid tumors.  Cancer 2001; 91:815-821.

 

  • Kunschner, LJ, Kuttesch J, Hess K, Yung WK. Survival and recurrence factors in adult medulloblastoma:  The M. D. Anderson Cancer Center experience from 1978 to 1998.  Neuro-Oncology 2001; 3(3):167-173.

 

  • Lacroix M, Abi-Said D, Fourney DR, Gokaslan ZL, Shi WM, DeMonte F, Lang FF, McCutheon IE, Hassenbusch SJ, Holland E, Hess KR, Michael C, Miller D, Sawaya R.  A multivariate analysis of 416 patients with glioblastoma multiforme:  prognosis, extent of resection, and survival.  Journal of Neurosurgery 2001; 95(2):190-198.

  • Munden RF, Hess KR. “Ditzels” on chest CT: survey of members of the Society of Thoracic Radiology. AJR American Journal of Roentgenology 2001; 176(6):1363-1369.

 

  • Pisters PW, Hudec WA, Hess KR, Lee JE, Vauthey JN, Lahoti S, Raijman I, Evans DB. Effect of preoperative biliary decompression on pancreaticoduodenectomy-associated morbidity in 300 consecutive patients. Annals of Surgery 2001; 234(1):47-55.

 

2000

 

  • Anderlik MR, Pentz RD, Hess KR. Revisiting the truth-telling debate: a study of disclosure practices at a major cancer center. Journal of Clinical Ethics 2000; 11(3):251-259.

 

  • Evans DB, Wolff RA, Hess KR. Adjuvant radiotherapy and 5-fluorouracil after curative resection of cancer of the pancreas and periampullary region. Annals of Surgery 2000; 232(5):727.

 

  • Lee JJ, Hess KR, Dubin JA. Extensions and applications of event charts. The American Statistician 2000; 54:63-70.

  • Levin VA, Uhm JH, Jaeckle KA, Choucair A, Flynn PJ, Yung WKA, Prados MD, Bruner JM, Chang SM, Kyritsis AP, Gleason MJ, Hess KR. Phase III randomized study of postradiotherapy chemotherapy with alpha-difluoromethylornithine-procarbazine, N-(2-chloroethyl)-N'-cyclohexyl-N-nitrosurea, vincristine (DFMO-PCV) versus PCV for glioblastoma multiforme. Clinical Cancer Research 2000; 6(10):3878-3884.

 

  • Meric F, Milas M, Hunt KK, Hess KR, Pisters PW, Hildebrandt G, Patel SR, Benjamin RS, Plager C, Papadopolous NE, Burgess MA, Pollock RE, Feig BW. Impact of neoadjuvant chemotherapy on postoperative morbidity in soft tissue sarcomas. Journal of Clinical Oncology 2000; 18(19):3378-3383.

 

  • Meyers CA, Hess KR, Yung WK, Levin VA. Cognitive function as a predictor of survival in patients with recurrent malignant glioma. Journal of Clinical Oncology 2000; 18(3):646-650.

 

  • Puduvalli VK, Kyritsis AP, Hess KR, Bondy ML, Fuller GN, Kouraklis GP, Levin VA, Bruner JM.  Patterns of expression of Rb and p16 in astrocytic gliomas, and correlation with survival. International Journal of Oncology 2000; 17(5):963-969.

 

1999

 

  • Bold RJ, Hess KR, Pearson AS, Grau AM, Sinicrope FA, Jennings M, McConkey DJ, Corazon D, Bucana CD, Cleary KR, Chiao PJ, Abbruzzese JL, Evans DB. Molecular and pathologic prognostic factors in resectable pancreatic cancer: p53 and bcl-2. Journal of Gastrointestinal Surgery 1999; 3:263-277.

  • Fuller GN, Rhee CH, Hess KR, Caskey L, Wang R, Bruner JM, Yung WKA, Zhang W. Reactivation of insulin-like growth factor binding protein 2 expression in glioblastoma multiforme: a revelation by parallel gene expression profiling. Cancer Research 1999; 59:4228-4232.

  • Groves MD, Maor MH, Meyers C, Kyritsis AP, Jaeckle KA, Yung WKA, Sawaya RE, Hess KR, Bruner JM, Peterson P, Levin VA.  A phase II trial of high-dose bromodeoxyuridine with accelerated fractionation radiotherapy followed by procarbazine, lomustine, and vincristine for glioblastoma multiforme. International Journal of Radiation Oncology, Biology, Physics 1999; 45:127-135.

  • Hess KR.  Extent of resection as a prognostic variable in the treatment of gliomasNeuro-Oncology 1999; 42:227-231.

  • Hess KR, Abbruzzese MC, Lenzi R, Raber MN, Abbruzzese JL. Classification and regression tree analysis of 1000 consecutive patients with unknown primary carcinoma. Clinical Cancer Research 1999; 5(11):3403-3410.

 

  • Hess KR, Serachitopol DM, Brown BW. Hazard function estimators: a simulation study. Statistics in Medicine 1999; 18:3075-3088.

  • Hess KR, Wong ET, Jaeckle KA, Kyritsis AP, Levin VA, Prados MD, Yung WK. Response and progression in recurrent malignant glioma. Neuro-oncology 1999; 1(4):282-288.

 

  • Pentz RD, Young LN, Amos CI, Hess KR, Wei Q, Anderlik MR. Informed consent for tissue research [letter]. Journal of the American Medical Association 1999; 282:1625.

  • Rhee CH, Hess KR, Ruiz M, Yang Y, Jabbur J, Chen S, Chenchik A, Fuller GN, Zhang W. cDNA expression array reveals heterogeneous gene expression profiles in three glioblastoma cell lines Oncogene 1999; 18:2711-2717.

  • Wong ET, Hess KR, Gleason MJ, Jaeckle KA, Kyritsis AP, Prados MD, Levin VA, Yung WKA. Outcomes and prognostic factors in recurrent glioma patients enrolled onto phase II clinical trials. Journal of Clinical Oncology 1999; 17: 2572-2578.