Kenneth R. Hess,
Ph.D.
Associate Professor
of Biostatistics
The University of Texas
M. D. Anderson
Cancer Center
Some recent publications:
2002
- Fuller
GN, Hess KR, Rhee CH, Yung WK, Sawaya RA,
Bruner JM, Zhang W. Molecular classification of human diffuse gliomas by multidimensional scaling analysis of gene
expression profiles parallels morphology-based classification, correlates
with survival, and reveals clinically-relevant novel glioma
subsets. Brain Pathology 2002; 12(1):108-116.
- Groves
MD, Puduvalli VK, Hess KR, Jaeckle KA, Peterson P,
Alfred Yung WK, Levin VA. Phase II Trial of Temozolomide
Plus the Matrix Metalloproteinase Inhibitor, Marimastat,
in Recurrent and Progressive Glioblastoma Multiforme. Journal of Clinical Oncology 2002;
20(5):1383-1388.
- Herrera
CA, Xu L, Bucana CD,
Silva el VG, Hess KR, Gershenson DM, Fidler IJ.
Expression of metastasis-related genes in human epithelial ovarian tumors.
International Journal of Oncology 2002; 20(1):5-13.
- Robins
HI, Chang SM, Prados MD, Yung WK, Hess KR, Schiff D, Greenberg H,
Fink K, Nicolas K, Kuhn JG, Cloughesy T, Junck L, Mehta M. A phase II trial of thymidine and carboplatin
for recurrent malignant glioma: A North
American brain tumor consortium study. Neuro-Oncology
2002; 4:109-114.
- Shmulevich I, Hunt D, El-Neggar
A, Taylor E, Ramdas L, Laborde
P, Hess KR, Pollock R, Zhang
W. Tumor specific gene expression profiles in human leiomyosarcoma. Cancer 2002; 94(7):2069-2075.
2001
- Baggerly KA, Coombes KR, Hess KR, Stivers
DN, Abruzzo LV, Zhang W. Identifying
differentially expressed genes in cDNA microarray experiments. Journal of
Computational Biology 2001; 8(6):639-659.
- Breslin TM, Hess
KR, Harbison DB, Jean ME, Cleary KR, Dackiw AP, Wolff RA, Abbruzzese
JL, Janjan NA, Crane CH, Vauthey
JN, Lee JE, Pisters PW, Evans DB. Neoadjuvant chemoradiotherapy
for adenocarcinoma of the pancreas: treatment
variables and survival duration. Annals of Surgical Oncology 2001;
8(2):123-132.
- Gutman H, Hess
KR, Kokotsakis JA, Ross MI, Guinee VF, Balch CM. Surgery
for abdominal metastases of cutaneous melanoma.
World Journal of Surgery 2001; 25(6):750-758.
- Hess KR, Abbruzzese
JL. Matrix metalloproteinase inhibition of pancreatic cancer: matching
mechanism of action to clinical trial design (Letter). Journal of Clinical Oncology
2001; 19(15):3445-3446.
- Hess KR, Fuller GN, Rhee CH, Zhang W. Statistical pattern analysis of gene
expression profiles for glioblastoma tissues and
cell lines. International Journal of Molecular Medicine 2001;
8(2):183-188.
- Hess KR, Zhang W, Baggerly KA, Stivers DN, Coombes KR. Microarrays:
handling the deluge of data and extracting reliable information. Trends in
Biotechnology 2001; 19(11):463-468.
- Hill
LR, Hess KR, Stephens LC, Price
RE, Gray KN. Correlation of kidney weight and volume and selected skeletal
parameters to sex in the adult rhesus monkey (Macaca
mulatta). Journal of Medical Primatology
2001; 30(1):56-60.
- Kozuch P, Hoff PM, Hess KR, Adams J, Newman RA, Lee F, Pazdur R. Phase I bioequivalency study of MitoExtra
and mitomycin C in patients with solid
tumors. Cancer 2001; 91:815-821.
- Kunschner, LJ, Kuttesch J, Hess K, Yung WK. Survival and
recurrence factors in adult medulloblastoma:
The M. D. Anderson Cancer Center experience from 1978 to 1998. Neuro-Oncology 2001; 3(3):167-173.
- Lacroix M, Abi-Said D, Fourney DR, Gokaslan ZL, Shi
WM, DeMonte F, Lang FF, McCutheon
IE, Hassenbusch SJ, Holland E, Hess KR, Michael C, Miller D, Sawaya R. A multivariate analysis of 416
patients with glioblastoma multiforme:
prognosis, extent of resection, and survival. Journal of
Neurosurgery 2001; 95(2):190-198.
- Munden RF, Hess
KR. “Ditzels” on chest CT: survey of members
of the Society of Thoracic Radiology. AJR American Journal of Roentgenology 2001; 176(6):1363-1369.
- Pisters PW, Hudec WA, Hess KR, Lee JE, Vauthey JN, Lahoti S, Raijman I, Evans DB. Effect of preoperative biliary decompression on pancreaticoduodenectomy-associated
morbidity in 300 consecutive patients. Annals of Surgery 2001;
234(1):47-55.
2000
- Anderlik MR, Pentz RD, Hess KR. Revisiting
the truth-telling debate: a study of disclosure practices at a major
cancer center. Journal of Clinical Ethics 2000; 11(3):251-259.
- Evans
DB, Wolff RA, Hess KR. Adjuvant
radiotherapy and 5-fluorouracil after curative resection of cancer of
the pancreas and periampullary region. Annals of
Surgery 2000; 232(5):727.
- Lee
JJ, Hess KR, Dubin JA. Extensions and applications of event charts.
The American Statistician 2000; 54:63-70.
- Levin
VA, Uhm JH, Jaeckle
KA, Choucair A, Flynn PJ, Yung WKA, Prados MD, Bruner JM, Chang SM, Kyritsis AP, Gleason
MJ, Hess KR. Phase III
randomized study of postradiotherapy
chemotherapy with alpha-difluoromethylornithine-procarbazine,
N-(2-chloroethyl)-N'-cyclohexyl-N-nitrosurea,
vincristine (DFMO-PCV) versus PCV for glioblastoma
multiforme. Clinical Cancer Research 2000;
6(10):3878-3884.
- Meric F, Milas M, Hunt KK, Hess KR, Pisters
PW, Hildebrandt G, Patel SR, Benjamin RS, Plager
C, Papadopolous NE, Burgess MA, Pollock RE, Feig BW. Impact of neoadjuvant
chemotherapy on postoperative morbidity in soft tissue sarcomas. Journal
of Clinical Oncology 2000; 18(19):3378-3383.
- Meyers
CA, Hess KR, Yung WK, Levin VA.
Cognitive function as a predictor of survival in patients with recurrent
malignant glioma. Journal of Clinical Oncology
2000; 18(3):646-650.
- Puduvalli VK, Kyritsis AP, Hess KR, Bondy ML, Fuller GN, Kouraklis GP, Levin VA, Bruner JM. Patterns of expression of Rb and p16 in astrocytic gliomas, and correlation with survival. International
Journal of Oncology 2000; 17(5):963-969.
1999
- Bold
RJ, Hess KR, Pearson AS, Grau AM, Sinicrope FA,
Jennings M, McConkey DJ, Corazon D, Bucana CD, Cleary KR, Chiao
PJ, Abbruzzese JL, Evans DB. Molecular and
pathologic prognostic factors in resectable
pancreatic cancer: p53 and bcl-2. Journal of Gastrointestinal Surgery
1999; 3:263-277.
- Fuller
GN, Rhee CH, Hess KR, Caskey L, Wang R, Bruner
JM, Yung WKA, Zhang W. Reactivation of insulin-like growth factor binding
protein 2 expression in glioblastoma multiforme: a revelation by parallel gene expression
profiling. Cancer Research 1999; 59:4228-4232.
- Groves
MD, Maor MH, Meyers C, Kyritsis AP, Jaeckle KA, Yung WKA, Sawaya
RE, Hess KR, Bruner JM,
Peterson P, Levin VA. A phase II trial of high-dose bromodeoxyuridine with accelerated fractionation
radiotherapy followed by procarbazine, lomustine, and vincristine for glioblastoma
multiforme. International Journal of Radiation
Oncology, Biology, Physics 1999; 45:127-135.
- Hess KR. Extent of resection
as a prognostic variable in the treatment of gliomas.
Neuro-Oncology 1999; 42:227-231.
- Hess KR, Abbruzzese
MC, Lenzi R, Raber MN,
Abbruzzese JL. Classification and regression
tree analysis of 1000 consecutive patients with unknown primary carcinoma.
Clinical Cancer Research 1999; 5(11):3403-3410.
- Hess KR, Serachitopol
DM, Brown BW. Hazard function estimators: a simulation study. Statistics
in Medicine 1999; 18:3075-3088.
- Hess KR, Wong ET, Jaeckle KA, Kyritsis AP, Levin VA, Prados
MD, Yung WK. Response and progression in recurrent malignant glioma. Neuro-oncology 1999;
1(4):282-288.
- Pentz RD, Young
LN, Amos CI, Hess KR, Wei Q, Anderlik
MR. Informed consent for tissue research [letter]. Journal of the American
Medical Association 1999; 282:1625.
- Rhee CH, Hess
KR, Ruiz M, Yang Y, Jabbur J, Chen S, Chenchik A, Fuller GN, Zhang W. cDNA expression array
reveals heterogeneous gene expression profiles in three glioblastoma cell lines Oncogene
1999; 18:2711-2717.
- Wong
ET, Hess KR, Gleason MJ, Jaeckle KA, Kyritsis AP, Prados
MD, Levin VA, Yung WKA. Outcomes and prognostic factors in recurrent glioma patients enrolled onto phase II clinical
trials. Journal of Clinical Oncology 1999; 17: 2572-2578.