[English] [Español] [Turkish] International View Help Department of Pathology Surgical and Autopsy Pathology Neuropathology and Diagnostic Hybridization Laboratory Immunocytochemistry and Electron Microscopy Cytopathology   Image Cytometry/FISH Diagnostic Laboratory Cancer Genomics Core Laboratory

Cancer Genomics Program The Cancer Genomics Program is a major initiative under the direction of Dr. Stanley Hamilton and supported by Dr. John Mendelsohn, president of M. D. Anderson Cancer Center. A Genomics Fund has been earmarked for the establishment of a Cancer Genomics Core Laboratory. Dr. Wei Zhang is the Director of the Core Laboratory. The Genomics Core Laboratory is currently focusing on establishment of two related core technologies, microarray technology and SAGE technology. Microarray technology allows us to build in-house gene chips tailored for different needs of organ-specific research programs. Both known genes from the Unigene database and expressed sequence tags (ESTs) can be spotted at a high density (5,000 to 10,000 genes) on genechips for gene expression profiling of cancers. Cancer gene expression profiling is anticipated to provide a molecular paradigm for cancer diagnosis and prognosis and to provide a molecular basis for individualized therapy in the future. SAGE technology allows discovery of novel genes that are important for cancer genesis. It is anticipated that the two technologies will greatly increase our power to understand the biology of cancer, which may lead to improved cancer therapy. For detailed information on the research program in Dr. Zhang's lab, please visit http://www.mdanderson.org/~genomics.