Section 3 - Disease related to treatment

Return to top of Section 3   or  Go back one page 

Diffuse necrotizing leukoencephalopathy

Click on image to enlarge
Image will open in a separate window 

Case 23  

A 22 year old male with ALL
Shortly after receiving intrathecal MTX and cranial irradiation, this patient developed personality changes and drowsiness. MRI (T2) demonstrates obvious periventricular hyperintensity consistent with necrotizing leukoencephalopathy. There was no enhancement. It may be that the term"necrotizing"should be reserved for the most severe cases or those that do not resolve. This patient was lost to follow up.

©2002 The Levit Radiologic - Pathologic Institute
1100 Holcombe Blvd, Houston, TX 77030
 (USA) / 713-792-2728     

Last updated; February 2002 - contact  Webmaster

©2002 The University of Texas M. D. Anderson Cancer Center
1515 Holcombe Blvd, Houston, TX 77030
1-800-392-1611 (USA) / 1-713-792-6161     Legal Statements