MM Learn
   Scientific Exhibits

   Soft-Tissue
  
Sarcoma Home

     Abstract

     Methods & 
    
Materials

     References

     Quiz

     Help

     Contact

 

 

 

MIMICS OF SOFT-TISSUE SARCOMA: PSEUDOTUMORS

INTRODUCTION

PIGMENTED VILLONODULAR SYNOVITIS (PVNS)

  • Proliferative Synovial Disorder
  • More common in young adults
  • Male > Female
  • Localized within Tendon Sheath (Nodular Synovitis)
  • Giant Cells - Giant Cell Tumor of Tendon Sheath
  • Intraarticular Synovial Membrane with Hemosiderin - (PVNS)
  • Possibility of Inflammatory, Neoplastic etiology
Click on image(s) to view JPEG image(s).
 

Patient 4
51-year-old male with surgically proven PVNS of right knee.

1.


Sagittal T1W MR image reveals nodular, lobulated intermediate signal intensity mass. It is uncommon for sarcomas to be intraarticular in location. Rarely synovial sarcomas may arise in intraarticular locations.

2.


Sagittal contrast enhanced T1W MR image reveals nodular low signal intensity foci within mass with areas of enhancement around individual nodules.

3.


Coronal T2W MR image reveals nodular high signal intensity focus. PVNS does not have to exhibit low signal intensity on T2W MR images to suggest this diagnosis.

4.


Photograph of the gross resected specimen superimposed on the sagittal MR image reveals the nodularity within the mass corresponding to the MR image.

5.


Photomicrograph (original magnification, X120, H-E stain) reveals the synovial villous proliferation and interspersed hemosiderin pigment characteristic of PVNS. Presence or absence of low signal intensity on T2W MR images may depend on histologic composition, stage of hemorrhage and amount of hemosiderin.

Copyright ©2003 All rights reserved.
The University of Texas M. D. Anderson Cancer Center
1515 Holcombe Blvd, Houston, TX 77030
1-800-392-1611 (USA) / 1-713-792-6161     Legal Statements
Last updated; September 2003
back start mimics menu end next