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| Databases - Bibliographic |
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| Carcinogenic Potency Database (CPDB) |
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This is a widely used resource on the results of chronic, long-term animal cancer tests. It provides a single, standardized and easily accessible database that includes sufficient information on each experiment to permit investigations into many research areas of carcinogenesis. Both qualitative and quantitative information on positive and negative experiments are reported, including all bioassays from the National Cancer Institute/National Toxicology Program (NCI/NTP) and experimental results from the general literature that meet a set of inclusion criteria. |
| Cancer Genetics Services Directory |
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This National Cancer Institute directory lists professionals who provide services related to cancer genetics (cancer risk assessment, genetic counseling, genetic susceptibility testing, and others). |
| ClinicalTrials.gov |
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The U.S. National Institutes of Health, through the National Library of Medicine, has developed ClinicalTrials.gov to provide patients, family members and members of the public current information about clinical research studies. The database can be searched by keyword or browsed by disease entity. |
| IARC Monographs Database on Carcinogenic Risks to Humans |
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The IARC Monographs series publishes authoritative independent assessments by international experts on the carcinogenic risks posed to humans by a variety of agents, mixtures and exposures. Since its inception in 1972, the series has reviewed more than 860 agents, and IARC Monographs have become well-known for their thoroughness, accuracy and integrity. |
| IARC TP53 Mutation Database |
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This database is made up of 3 parts, the Somatic Mutation Database, the Germline Mutation Database and a List of Common Polymorphisms. The Somatic Mutation Database contains exclusively p53 mutations associated with human cancers that have been identified by sequencing and published in the peer-reviewed literature. The Germline Mutation Database contains information on families fulfilling the definition of Li Fraumeni and Li Fraumeni-related syndromes and on individuals carrying a germline mutation in the TP53 gene. The list of polymorphisms is a simple table that describes the DNA sequence variants (polymorphisms) that have been observed in the human population. |
| International Cancer Research Portfolio |
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The International Cancer Research Portfolio, or ICRP, represents a database of information on cancer research awards of the cancer funding organizations that comprise the Common Scientific Outline (CSO) Partners. Created as a means for CSO Partner organizations to share information about current and ongoing cancer research, the ICRP public web site allows the public at-large to view and browse information about research supported by cancer funding organizations
in the United States (US) and the United Kingdom (UK). Information contained in this site includes research abstracts for most active awards funded by three of the CSO Partner organizations. These awards may be
searched by cancer type, by broad scientific area, by location (i.e. state or country), by funding organization and by recipient institutions. Each of the three organizations submitting data for this first phase of ICRP has provided the most up-to-date portfolio available. The time windows of the research differ according to the policies and procedures of each organization. |
| National Cancer Data Base |
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The National Cancer Data Base (NCDB) is a nationwide oncology outcomes database for over 1,500 hospitals in 50 states, and is in its 10th year of operation. The NCDB was founded as a joint project of the Commission on Cancer (CoC) of the American College of Surgeons (ACOS) and the American Cancer Society (ACS). |
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| Databases - Biological & Genetic |
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| Anti-cancer Agent Mechanism Database |
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The Anti-cancer Agent Mechanism Database is a set of 122 compounds with anti-cancer activity and a reasonably well known mechanism of action. |
| CCRIS: Chemical Carcinogenesis Research Information System |
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This database provides carcinogenicity, mutagenicity, tumor promotion, and tumor inhibition data provided by the National Cancer Institute. |
| cDNA xProfiler |
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The cDNA xProfiler is a tool that compares gene expression between two pools of libraries. For a gene to be "present" in a library pool, there must be at least one EST sequence found in the UniGene cluster for that gene. |
| DGED: Digital Gene Expression Displayer |
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The Digital Gene Expression Displayer is a tool that compares gene expression between two pools of libraries. In contrast to the xProfiler, the DGED treats the presence of a gene in a library pool as a matter of degree. It compares the "degree" of presence of a gene in pool A with its "degree" of presence in pool B. |
| Familial Cancer Database |
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This database provides software to assist with differential diagnosis in familial cancer. It is free but requires registration, downloading and installation of the software and data. Please use your own computer for this database. |
| FISH-mapped BACs |
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CGAP is generating a set of Bacterial Artificial Chromosome (BAC) clones (available to the public) that have been mapped cytogenetically by fluorescence in situ hybridization (FISH) and physically by sequence tagged sites (STSs) to the human genome. The BAC data is integrated into various CGAP and NCBI databases to provide related clinical, histopathologic, genetic, and genomic information. |
| Gene Finder |
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The Gene Finder tool finds one gene or list of genes, based on selected search criteria. Each "found" gene is linked to a Gene Info page which provides selected gene data and links to various NCBI and NCI databases. |
| GeneMap99 |
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A new human gene map from the International RH Mapping Consortium. Each chromosome is displayed with RH Map GB3 and GB4, the genetic map, gene density and a cytogenetic ideogram. |
| GLS: Gene Library Summarizer |
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The GLS Tool finds all the genes expressed in a single cDNA library or group of cDNA libraries. It then classifies the genes as unique or non-unique, and then further identifies the genes in each of these groups as known or unknown. |
| GO Browser |
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The Genetic Ontology Browser classifies human and mouse genes by molecular function, biological process, and cellular component. This database is best viewed in Internet Explorer and must be accessed from the outlink page that you are taken to. |
| Library Finder |
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The Library Finder tool can find a single cDNA or SAGE library or a group of libraries, depending on the search criteria selected. The search first returns a Library List page, from which each library is linked to its own Library Info page. This page contains sequence and clone information and details of the library's preparation. |
| Mitelman Database of Chromosome Aberrations in Cancer |
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The information in the Mitelman Database of Chromosome Aberrations in Cancer relates chromosomal aberrations to tumor characteristics, based either on individual cases or associations. The Cancer Genome Anatomy Project has developed 5 tools to help with analysis of information in this database. |
| MMHC Cancer Models Database |
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The Mouse Models of Human Cancer database can be queried for models submitted by fellow researchers. Information about the making of models, their genetic description, histopathology, derived cell lines, associated images, carcinogenic agents, and therapeutic trials can be retrieved. Links to associated publications and other resources are provided. |
| Nucleotide BLAST |
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The Basic Local Alignment Search Tool (BLAST) is a set of specialized search programs which find similarities between either protein or nucleotide sequences. Here, CGAP provides an alternative interface to this tool to specifically ask whether a DNA sequence is similar to any UniGene clusters. If a gene similarity is found, a link to the Gene Info page is provided. |
| Online Mendelian Inheritance in Man (OMIM) |
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This database is a catalog of human genes and genetic disorders and has been developed for the World Wide Web by NCBI, the National Center for Biotechnology Information. This database contains textual information, pictures, and reference information. It also contains copious links to NCBI's Entrez database of MEDLINE articles and sequence information. |
| Recurrent Chromosome Aberrations in Cancer |
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The recurrent aberrations were derived from the Mitelman Database of Chromosome Aberrations in Cancer (2002) and include all cytogenetic changes present in at least two cases of the same morphologic entity, and, whenever applicable for solid tumors, within the same site. The complete karyotypes, patient characteristics, and references are found in the Mitelman Database of Chromosome Aberrations in Cancer. |
| SAGEmap |
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Serial Analysis of Gene Expression (SAGE) SAGEmap is a SAGE data resource for the query and retrieval and analysis of SAGE data from any
organism. The data can be searched by tag, by sequence, by gene, by library and by Request Id. |
| SNP Gene Viewer |
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The Gene Viewer is a graphical display tool. Both CGAP SNPs and SNPs submitted to the NCBI dbSNP database by other investigators are shown in the context of transcripts, open reading frames and protein motifs. |
| SNP500 Cancer |
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The goal of the SNP500Cancer project is to resequence 102 reference samples to find known or newly discovered single nucleotide polymorphisms (SNPs) which are of immediate importance to molecular epidemiology studies in cancer. SNP500Cancer provides a central resource for sequence verification of SNPs. |