MD Anderson Cancer Center
Genetic Risk Found for Lung Cancer
Two separate inherited genetic variations raise smokers' and ex-smokers risk of developing lung cancer by 28 to 81 percent. Smoking is the lead factor heightening lung cancer risk, but less than 20 percent of smokers actually develop the disease. Finding the genes involved should help us understand the mechanisms that actually trigger lung cancer and identify people who are at higher risk. The result should be better screening, prevention and, ultimately, treatment. Among potential genes involved are three nicotine receptors.

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Title: Genetic Risk Found for Lung Cancer
Summary: Two separate inherited genetic variations raise smokers' and ex-smokers risk of developing lung cancer by 28 to 81 percent. Smoking is the lead factor heightening lung cancer risk, but less than 20 percent of smokers actually develop the disease. Finding the genes involved should help us understand the mechanisms that actually trigger lung cancer and identify people who are at higher risk. The result should be better screening, prevention and, ultimately, treatment. Among potential genes involved are three nicotine receptors.
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