Section
of Neuropathology
The
Section of Neuropathology is dedicated to providing accurate,
rapid and efficient diagnoses for the MDACC brain tumor patients
as well as maintaining interdepartmental research collaborations
and providing education for trainees. Continued success, productivity,
diagnosis, and research depend upon the education of others.
Neuropathology receives more than 1200 brain and spinal cord biopsies
for diagnosis per year. The research commitment includes development of genetic markers
for patient tests for diagnostic and prognostic significance, better methods of brain
tumor classification, and investigation of spatial-temporal pathways and modes of
spread of tumors within the brain.
The activities carried out in the laboratory are patient care and
research related. These activities include paraffin and frozen tissue sectioning,
hematoxylin and eosin staining, immunohistochemical staining, in-situ hybridization
techniques, HPV Capture procedures and silver nitrate stains. A bank of frozen brain
tumor samples has been maintained for almost 15 years. Researchers are supplied with
tissue for their various research protocols from this tumor bank.
Annually 15,600 tests areperformed including
more than 1500 in situ slides per year and 800 viral
profile tests for HPV. This Section includes four board certified
neuropathologists, and one senior secretary. The Neuropathology/
Hybridization Laboratory has three certified histotechnology
technicians and one research assistant.
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Neuropathology, Immunohistochemistry,
and Diagnostic Hybridization Laboratory Staff
1st row (L-R):
Sabina Magedson, Maria Grimbert, Gerry Quiñones, Lauren A. Langford,
M.D., Janet M. Bruner, M.D., Swarajya Chaliki, Suneetha Inampudi,
Sharon LeBlanc
2nd row (L-R): Greg Fuller, MD, Annette Basey, Brenda
Johnson, Ken Aldape, MD, Ann Miller, Nelson Ordòñez, MD, Janet Quiñones
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