Section 1 - Direct leukemic involvement of the Central Nervous System

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Meningeal disease: Leukemic infiltration of the meninges

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Case 3

A 46 year old with ALL
Axial contrast enhanced MR image shows focal subarachnoid leukemic deposits (arrows). Areas of more generalized meningeal disease could be seen at other levels. Focal deposits such as these in the subarachnoid space are not as common as more diffuse meningeal disease, and if unaccompanied by other areas of more generalized involvement, may be difficult to differentiate from focal dural leukemic masses or even parenchymal disease.

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