Upcoming and Recent Events
James S. McDonnell Foundation has awarded a 3-year grant to Dr. Wei Zhang to investigate a new tumor suppressor gene IIp45.
Dr. Zhang has been invited to present at the World Cancer Congress of UICC in Geneva.
Dr. Zhang gave a presentation on sarcoma genomics at Tianjin Cancer Institute and Hospital.
New graduate students Monica Linan and Umadevi Thirumurthi will join the lab for their rotations in the Fall 2008 and Spring 2009 respectively.
Yingmei Wang will join the lab in Oct as a visiting student on a scholarship from the Education Council of China.
Scientific American has published a special edition on Cancer with an AACR advertisement featuring Drs. DuBois (AACR president) and Zhang.
Kristen's abstract has been accepted for presentation at the 2008 Society of Neuro-Oncology conference.
Marianne and Ken Bouldin of NFCR Hope Fund and Sree Kumar of NFCR came to MDACC to join a special progress report of MPNST research presented by Drs. Dina Lev and Wei Zhang groups. Antti presented the array CGH project. (July 18th)
Antti Ylipaa has moved to ISB in Seattle to work with Ilya Shmulevich.
Drs. Zhang and Hamilton chaired the second MDACC Cancer Genomics Minisymposium sponsored by Agilent. 9:30 am - 2 pm, July 15th, 2008. Nine MDACC investigators and an Agilent informatician presented. More than 100 people attended. The minisymposium highlighted 9 projects supported by the Cancer Genomics Core Laboratory. One project led by Dr. Yinling Hu's group just had a paper accepted by Cancer Cell.
Drs. Zhang and Fuller have been awarded a three year Goldhirsh Foundation grant to study IGFBP2-ILK pathways in glioma.
Dr. Zhang has become a regular member of the NIH Cancer Genetics Study Section.
Jheir was nominated to receive an one-year AAAS/Science Memberships.
Jheri Dupart was a finalist in the Trainee Research Day. Congratulations
Drs. Zhang and Fuller presented at the Pathology in the 21st Century conference. May 2-3, 2008. Houston, TX.
Sarah has left for UT Austin for her second postdoc training.
Antti Ylipaa has joined the lab from Finland for a few months.
Dr. Zhang presented at the Croucher Advanced Study Institute "Mathematical and Algorithmic Challenges for Modeling and Analyzing Modern Data Sets" in Hong Kong, 21-25 April 2008.
Dr. Zhang presented at the China Southern Genome Center, Shanghai, April 26, 2008.
Jheri Dupart has received the Sowell Huggins Scholarship from the graduate school. Congratulations
Sarah Dunlap has received the Trainee Excellence Award at MDACC. Congratulations
Vice President Ying Wang led the third delegation from Tianjin Cancer Hospital and Institute to visit MDACC.
Dr. Zhang presented at the Fourth Annual Neurooncology Symposium "Innovations in Neurooncology". Hackensack University Medical Center, Hackensack, New Jersey March 28, 2008.
Dr. Zhang participated in the Cancer Genome Atlas workshop at NCI: Genomics and Biology of GBM. NCI, Bethesda, Maryland, March 24-25, 2008
Dr. Zhang and colleagues (Fuller, Dougherty, Hess) has been awarded a patent on March 11, 2008. US patent 7,341,552: Strong Gene Sets for Glioma Classification
Kristen Holmes has received a fellowship from the NIH Pharmacoinformatic Training Grant and been appointed a Keck Fellow. Congratulations.
Kristen Holmes received the 1st Prize in the poster competition at the 2008 Cancer Biology Program Retreat. Congratulations.
Dr. Zhang has been awarded a grant from NFCR Hope Fund to work on a pilot genomic study on Malignant Peripheral Nerve Sheath Tumors (MPNST).
Dr. Zhang was invited to present in the Department of Physiology at the UT Southwestern in February 2008.
Dr. Jim Li, a neuropathology fellow, joined the lab to work on research projects for 7 months.
Sarah Dunlap and Kristen Holmes submitted two abstracts to the 2008 Annual AACR Symposium.
Sarah has successfully defended her PhD thesis on November 28th. Congratulations! Sarah will continue as a postdoc for a few months.
US Patent office has issued a patent (#7,257,563) on August 14th 2007 to Ilya Shmulevich, Edward Dougherty, and Wei Zhang. The patent is entitled "Probabilistic Boolean Networks."
Dr. Lynette Moore, who recently graduated from Baylor College of Medicine, has joined the lab as a postdoctoral fellow.
New graduate students Heather Highland and Qin Li have joined the lab for their first rotation. Huijuan Song will join the lab for the third rotation.
National Foundation for Cancer Research has awarded a two-year grant to Drs. Wei Zhang and Stanley Hamilton to study the role of NGAL in colon cancer.
Dr. Zhang was invited to present at the 4th International Think Tank Forum: Anti-Cancer Innovation and Global Collaboration on November 14-16, 2007 in Hong Kong. Organized by National Foundation for Cancer Research. For information, http://www2.nfcr.org/site/R?i=IV2Bi46-DswGv1XJfEP6Ww.
Sarah has been reappointed as an American Legion Auxiliary Fellow in Cancer Research for the 2007-2008 academic year. Congratulations.
Dr. Zhang has joined the Editorial Board of Comparative and Functional Genomics.
Dr. Zhang presented "Identification and validation of diagnostic markers and therapeutic targets" at the 5th National Conference on Oncology for Young Investigators, Chinese Medical Association, September 14-16, 2007. Lanzhou, China.
Dr. Zhang presented "Cancer Genomics and Cancer Systems Biology: Identification and validation of diagnostic markers and therapeutic targets" at the World Cancer Conference: Cancer Research & Cancer Drug Discovery. September 13-14, 2007. Beijing, China. For program please see: www.ibcchina.com.cn
Jheri Dupart's NIH predoctoral fellowship has been renewed for the thrid year. Congratulations.
Former postdoctoral fellow, Rongcai Jiang, has received a NSF grant in China to continue his work started in our lab. His most recent paper has been accepted for publication in Cancer Biology and Therapy.
Sarah Dunlap has been selected to attend the Second Annual NIH National Graduate Student Research Festival and present a poster. The event is scheduled for October 11 - 12, 2007 on the main campus of the NIH in Bethesda, MD.
Dr. Zhang was invited to present "Modeling of Genetic Regulatory Networks: a Data-Driven Process" at the conference "Computational Methods in Biomolecular Structures and Interaction Networks" Institute for Mathematical Sciences, National University of Singapore, Singapore, July 15-21, 2007.
A paper by graduate student Sarah Dunlap et al. has been published in the Proc Natl Acad. Sci USA. MDACC has issued a news release on this story. Other authors include Celestino J, Wang H, Jiang R, and Holland E. Drs. Greg Fuller and Wei Zhang are senior authors.
Dr. Ying Wu joined the lab as an Instructor.
Dr. Zhang gave a presentation on Cancer Genomics and Cancer Systems Biology at the Tianjin Medical University General Hospital. Dr. Zhang also gave a presentation on "Comparative Graduate Education in the US and China" at Tianjin Medical University. June 2007.
Sarah Dunlap won 1st Place, MD Anderson Alumni and Faculty Association Graduate Student Award in Clinical/Translational Research. MDACC Trainee Recognition Day Research Competition. She gave a platform presentation on May 25th, 2007. Sarah won the second prize at the same event of last year.
Kristen Holmes has joined the lab for her PhD thesis.
Robin Henry has joined the lab for her third rotation in GSBS.
After 1.5 years' successful research, Kanchana has left the lab and will pursue a new teaching opportunity close to home. Her second paper has recently been submitted.
George Wang officially received his PhD degree at the Graduation Ceremony and will be leaving for New York for Internal Medicine internship at Mt Sinai Medical School, New York 2007
Kanchana's protein lysate array paper has been published in Journal of Proteome Research. An interview of Dr. Zhang about this article will be profiled in an article in BioScience Technology.
Dr. Ping Ji will join the lab as an Instructor in July
Kexin Chen, the Chief of Epidemiology at Tianjin Cancer Hospital finished her work at MDACC and returned to Tianjin. She was at Dr. Qingyi Wei's group for one year and three months working on a collaborative project between Dr. Wei and Dr. Zhang. She has one paper in press in Clinical Cancer Research and one paper submitted ot Carcinogenesis.
Former postdoc Mustafa Akkiprik has received his first funding from TUBITAK (Scientific Research&Technology Council of Turkey. He is a faculty member at Marmara University, School of Medicine.
Former postdoc Rongcai Jiang has been recruited as an Associate Professor and Staff Director at the Tianjin Medical University General Hospital.
Dr. Zhang presented Brain Tumor Research, an overview at the "Together in Hope" National Brain Tumor Patient conference. Houston, TX, May 20, 2007.
Sarah Dunlap and Limei Hu presented two posters at AACR in LA this May. Drs. Xishan Hao and Ying Wang led a Chinese Anti-Cancer Association delegation and participated in AACR. Yumei Feng, who worked in our lab for a year, also presented a poster at AACR on her breast genomics studies, which is in press in Breast Cancer Research and Treatment.
Dr. Jon Trent chaired an institutional grand rounds on sarcoma research. Drs. Trent and Zhang presented their work on sarcoma pharmacogenomic studies.
Dr. Zhang participated in a panel presentation and discussion on Cancer Metastasis at the Eighteenth Annual Cancer Progress Conference, March, New York.
Our sarcoma genomics paper by Price et al. is published in PNAS. In this paper, we report a pair of robust and highly accurate markers for differentiating gastrointestinal stromal tumor (GIST) and leiomyosarcoma. This is a collaborative project between MDACC and Institute for Systems Biology. At MDACC, Drs. Zhang, Trent, El-Naggar, Hunt, and Pollock as well as Core Lab researcher Cogdell and Taylor participated in the investigation. At ISB, Price, Hood, and Shmulevich participated in this research. A news release was issued by MDACC and by the Institute for Systems Biology.
Sarah received the third prize at the Cancer Biology Program Retreat for her presentation.
Sarah received a travel award from graduate school to present a poster on IIp45 gene at the upcoming AACR.
Woonyoung Choi has been promoted to Instructor in the Department of Cancer Biology. Congratulations and best wishes.
Dr. Xishan Hao, the academician of the Chinese Academy of Engineering and President of Tianjin Medical University, visited MDACC after a meeting in San Antonio in preparation for the 4th World Congress of Breast Health to be held in Tianjin 2007.
A special issue on Cancer Genomics with Dr. Zhang as the guest editor was published in December in journal Technology in Cancer Research & Treatment. Former postdocs Mustafa and Daniel have a paper on breast cancer signal transduction pathways using protein lysate array in this special issue.
In the Society for Neuro-Oncology meeting, Sarah gave two platform presentations, Dr. Zhang gave a platform presentation for George Wang. Two additional posters were presented as well from our group.
Dr. Zhang chaired an Institutional Grand Rounds on Cancer Systems Biology on November 10. Drs. Zhang, Trent, and Freireich presented. Dr. Freireich has worked at MDACC for 41 years!
Dr. Ming Guo's paper on HPV detection in cervical cancer using real-time PCR conducted in our Core Lab has been e-published by Modern Pathology.
George Wang successfully defended his PhD thesis on Oct 6th. Congratulations Dr. Wang!
Rongcai Jiang finished his 2.5 years postdoc fellowship on Oct 4th and will return to China this month. Daniel Nicorici completed his 6 month postdoc fellowship with us and returned to Finland.
Dr. Zhang was invited to present Cancer Systems Biology at The University of Texas Medical Branch at Galveston. Galveston, Texas. September 29th, 2006.
Sarah was appointed as an American Legion Auxiliary Fellow in Cancer Research for the 2006-2007 academic year. Congratulations.
Two incoming graduate students of GSBS, Kristen Holmes and Borislava Tsanova, have joined the lab for a rotation.
Ellen Taylor and family have moved back to Indiana. Ellen worked in our lab for 6 years and contributed to many projects and co-authored a number of papers. Also, Dr. Yuan Pan has finished his 1 year work in our lab and will return to Tianjin Cancer Hospital.
The 4th Chinese Conference on Oncology will be held during Oct 26-29, 2006 in Tianjin, China. Dr. Zhang will give a presentation on cancer systems biology at the conference. For information, please e-mail: info@cco2006.org.
Dr. Shmulevich, who has moved to ISB in Seattle, was recently profiled in the magazine The Scientist.
The paper by Dr. Trent et al on induction of IGFBP3 by Gleevec in GIST has been published in Cancer.
Dr. Zhang received a grant from the Goldhirsh Foundation to study glioma systems biology.
Dr. Wei Zhang has been invited to guest edit a special issue of Microarrays in Cancer Research for Technology in Cancer Research and Treatment. (December issue)
Stanford student Rakesh Amaram is working with Sarah Dunlap this summer as a volunteer.
Mustafa Akkiprik completed his one year postdoc training and has returned to Turkey to start his laboratory at the Marmara University in Istanbul.
George Wang has gone back to University of Texas Medical School to complete his last year for his MD degree.
Dr. Wei Zhang presented colon cancer genomics at the M. D. Anderson Physicians Network 2nd Annual Cancer Symposium at Kauai, scheduled for June 26-30, 2006
Drs. Xishan Hao and Ying Wang visited MDACC to sign the sister institute agreement between Tianjin Medical University Cancer Institute and Hospital with MDACC. A signing ceremony was held on June 7th where Dr. Hao and Dr. Mendelsohn signed the agreement. Dr. Hao also presented the Tianjin cancer epedemiology studies the following day at the MDACC sister institute conference. At the July conference of UICC (International Union Against Cancer), Dr. Hao was elected to the board of directors.
Rongcai's paper is out in Proteomics and it is highlighted on the cover.
Sarah received the second prize for the MDACC Trainee Recognition Day platform competition.
Drs. Wei Zhang and Stanley Hamilton chaired a minisymposium on Cancer Genomics at MDACC on May 17, 2006. This symposium was rescheduled to this new date because of Rita.
Jheri has passed her oral exam unconditionally.
George will complete his PhD program and return to the last year in medical school in July. George is scheduled to defend his thesis before October.
Dr. Wei Zhang is invited to present at the 5th annual Symposium on Systems Biology, April 2006, Seattle, WA
Dr. Zhang is giving a presentation at Samsung Medical Center on April 14th.
Sarah gave a platform presentation at AACR. She is one of few graduate students who have received Scholar-in-Training Grant and presented at a minisymposium.
Tennis Star James Blake came to visit the lab. He is donating money to support GI cancer research.
George and Limei's paper on IGFBP2/integrin alpha 5 is in press in Journal of Biological Chemistry. Congratulations!
Dr. Wei Zhang gave a presentation at the World Microarray Congress in Vancouver, Canada.
Woonyoung's paper on SSAT regulation by NFkb is in press in Molecular Carcinogenesis.
Jheri has passed her written test as part of her qualifying exam.
The second edition of book "Computational and Statistical Approaches to Genomics" edited by Drs. Wei Zhang and Ilya Shmulevich has been published by Springer.
Sarah is presenting her work at the USCAP conference in Atlanta, February 14, 2006.
Sarah won an AACR-AFLAC, Incorporated Scholar-in-Training Award to present at 2006 AACR annual meeting. Only 10% applicants received the award. Congratulations.
Sarah won the third prize at the Cancer Biology Retreat. Congratulations.
Jheri has received the Minority Faculty Association (MFA) Scholarship: Jones/Wharton Cancer Research Scholarship, Texas Medical Center, 2006.
Matt and Sarah's paper on Shrew1 gene is featured on the cover of Cancer Biology and Therapy, March issue of 2006.
Sarah has been selected for a platform presentation at the 2006 AACR symposium, Washington, DC, April 2006.
The President of Tianjin Midical University and Cancer Hospital, Dr. Xishan Hao visited our group.
Sarah has been selected to give a platform presentation at the 2006 USCAP symposium, Atlanta, February 2006.
Sarah received a travel award from GSBS to present at the USCAP meeting
Sarah successfully passed her qualify exam. Now it is time to get some real work done:=)
Wei Zhang has been invited to serve as a section editor of Molecular Pathology, Archives of Pathology and Laboratory Medicine)
Matt and Sarah's paper on Shrew 1 gene in oligodendrogliomas has been accepted for publication in Cancer Biology and Therapy. Rongcai and Cristian's glioma signal transduction paper with lysate array technology is in press in Proteomics.
Cristian Mircean has successfully defended his PhD thesis and will work as a postdoc under Dr. Dougherty in 2006.
Yumei Feng has completed her 1-yr work at MDACC and returned to Tianjin Cancer Institute and Hospital.
Dr. Wei Zhang presented at the conference "ANIMAL MODELS OF HUMAN MALIGNANCIES AND BIOTHERAPIES" organized by European Commission's Marie Curie Actions Programme. Budapest, Nov 25-27.
Dr. Wei Zhang is invited to present at the Second Workshop on Models for Genetic Regulatory
Networks, Texas A&M University, November 7/8, 2005
Jheri Dupart has received a Minority Scholar travel award to attend and present at the AACR-NCI-EORTC International Conference "Molecular Targets and Cancer Therapeutics" to be held in Philadelphia during Nov 14-18.
Dr. Wei Zhang is invited to present a talk "Application of genomics and preteomics in cancer research" at the international conference on Anti-Cancer Innovations: Research for a Cure. October 13-15, 2005. Beijing, China. Organized by National Foundation for Cancer Research and the Chinese Academy of Medical Sciences.
Dr. Kanchana Natarajan joins the lab as an Instructor.
Sarah is selected to give a platform presentation at 2nd International conference on Tumor Progression & Therapeutic Resistance, Boston, Sept 18-20.
Drs. Wei Zhang and Stanley Hamilton are awarded a 2-year research grant from National Foundation for Cancer Research to study colon cancer biology.
Dr. Wei Zhang presented at the Institute of Biocomplexity and Informatics Conference on Systems Biology. August 27-31, Calgary, Canada.
Dr. Yuan Pan, M.D., PhD, a colon cancer surgeon in Tianjin Medical University Cancer Institute and Hospital, joined the lab in August on a Norvatis-M. D. Anderson Cancer Center fellowship.
Angela McMillian, a graduate of UT, joined the lab.
Sang Lee joined the lab for a summer internship.
A concept grant from DOD (Army breast cancer program) has been awarded to Wei Zhang.
Mustafa Akkiprik, Ph.D. joined the lab as a postdoc to work with Drs. Ayse Sahin and Wei Zhang.
The book "Genomic and Molecular Neuro-Oncology" edited by Wei Zhang and Gregory Fuller has been translated into Chinese by Dr. Peiyu Pu and colleagues and published in China.
Woonyoung Choi presented her work on polyamine pathway in colon cancer therapeutics in Samsung Medical Center, Seoul, Korea, July, 2005.
Woonyoung Choi presented a poster at the Gordon Research Conference on Polyamines, June, 2005.
Wei Zhang presented at the Samsung Medical Center in Seoul, Korea, June 13, 2005.
Wei Zhang presented at the Korean Cancer Hospital in Seoul, Korea, June 14, 2005.
Wei Zhang presented "Understanding Cancer Systems" at the annual conference of the China Cancer Association in Dalian, China, June 2-5, 2005.
Jheri Dupart has successfully competed for a NIH predoctoral fellowship. Congratulations..
Hubert Nguyen joined the lab as a volunteer for the summer.
Ying Zhao is retiring after working at MDACC for 15 years. Congratulations and enjoy.
Denise Juroske has completed her rotation as part of the training program from UTMDACC School of Health Sciences under the direction of Ellen Taylor, who is an adjunct faculty.
Lynsey Proctor has gone to Medical School at UTMB.
Dr. Xishan Hao, the president of Tianjin Medical University and its Cancer Institute and Hospital, a member of the Chinese Academy of Engineering, visited MDACC and our lab. Dr. Hao was invited to attend the MDACC Sister Institution conference.
Sarah Dunlap has received a NIH Pharmacoinformatics Predoctoral Fellowship and has been appointed as a Keck Fellow. Congratulations.
Wei Zhang has been invited to present at the "Together we hope” National Brain Tumor Patient conference. Houston, TX, May 2005
Woonyoung Choi, George Wang, and Sarah Dunlap will present at the upcoming AACR annual meeting in April.
Wei Zhang has been invited to present "Dissecting Cancer Invasion and Metastasis through Genomics" at the IEEE International Workshop on Genomic Signal Processing and Statistics, May 22-24, 2005, Rhode Island. Ilya Shmulevich, Edward, Dougherty, and Stu Kauffman will also be presenting.
Wei Zhang has been invited to present at the 2005 International Symposium on Breast Cancer, April 17-19, 2005, Tianjin, China
Jiyuan Sun has joined the lab to work on his PhD thesis. Welcome.
Lynsey Proctor has been accepted by the University of Texas Medical Branch in Galveston to start her medical career. Congratulations!
Albert Huang will transfer to the University of Washington and join Dr. Shmulevich at ISB for his PhD study.
Ilya Shmulevich has been recruited to the Institute of Systems Biology (ISB) as an Associate Professor beginning in April. ISB, directed by Dr. Leroy Hood, is a leader in systems biology. Congratulations!
Wei Zhang presented a seminar on "Regulation of Cancer Invasion by IGFBP2 and IIp45" at Sidney Kimmel Cancer Center in San Diego on Feb 2, 2005.
Sonya Song has received an offer to become the Project Director in the Division of Cancer Medicine of MDACC starting on Feb 1st. Congratulations on the career advancement.
Harri, Ilya, Valerie paper on In silico microdissection of microarray data from mixed cell populations has been accepted by BMC Bioinformatics.
Ilya Shmulevich has been invited to present at the Keystone conference on Systems Biology this April.
Cristain and Rongcai presented two posters at the Oncogenomics 2005 conference held in San Diego, Feb 2-6, 2005.
Sonya's paper on IIp45 splicing has been accepted by Cancer Res.
Cristian presented the protein lysate array poster (co-authored by Ilya, Ioan, Dave, Jack, Woonyoung, Stan, Wei) at CHI Protein Array Pep-talk and won the “Best Scientific Poster Award, San Diego, January 10, 2005.
Professor Ollio Yli-Harja from Finland has begun his 3 month sabatical in our lab.
Joseph Celestino has joined the lab on a part-time basis to support the glioma animal model project.
Graduate Student Binbin Deng has joined the lab for a rotation.
Woonyoung Choi's paper on colon cancer has been e-published in J. Biol Chem. Congratulations.
Core Lab has completed a Tumor Cell Line protein array that contains 90 different cancer cell lines. This array is available to all MDACC investigators. We have also completed a glioma array with 90 different glioma tissues.
A paper on protein lysate array analysis by Cristian Mircean, Ilya Shmulevich etc has been published on-line by Bioinformatics.
Yumei Feng, a research investigator from Tianjin Cancer Hospital is joining the lab for six months.
Wei Zhang is invited to present at U Mass Cancer Center on Oct 26, 2004.
George Wang's review article on cancer invasion is in press in Histology and Histopathology
Matti Nykter, a graduate student from Tampere University of Technology, Institute of Signal Processing, Finland joined the lab to work with Dr. Shmulevich for six months.
Ilya Shmulevich gave a presentation at the Toxicogenomics International Forum 2004, October 12-13, Japan
A paper to be publised in the first issue of a new journal: Trent J, Dupart J, and Zhang W. Imatinib mesylate: Targeted therapy of gastrointestinal stromal tumor. Current Cancer Therapy Reviews (in press)
Dr. Shmulevich (PI) and Dr. Zhang (co-PI) received a new RO1 to study genetic regulatory network.
The paper we published in BMC Genomics entitled "Improving signal intensities for genes with low-expression on oligonucleotide microarrays" has been accessed 1587 times up till Sept 29 based on BioMed Central statistics.
Wei Zhang is featured on the Author Profiles of BioMed Central http://www.biomedcentral.com/pioneer/profiles/.
First year graduate students Jiyuan Sun and Qianghua Xia joined the lab for rotation. Welcome.
Matt McDonald successfully defended his PhD thesis on July 28th. Congratulations! Matt is doing a postdoctoral fellowship with Dr. Aldape.
Dr. Jon Trent has successfully competed for an NIH K23 grant with Dr. Wei Zhang as the research mentor. Congratulations!
Shmulevich and Kauffman published a paper entitled "Activities and Sensitivities in Boolean Network Models," in Physical Review Letters.
Two new papers are published in Cancer Research by investigators with our Core Lab support.
Wei Zhang has been appointed as a Visiting Professor in the Beijing Neurosurgical Institute in July 2004.
John Dougherty has finished his summer research work and returned to Texas A&M.
Wei Zhang and Ilya Shmulevich have been accepted as Keck Faculty Fellows.
Eun-Ju Lee finished her research rotation and returned to Korea Samsung Medical Center.
Hua Wang has received a DOD postdoctoral Fellowship and will start her second postdoctoral fellowship at Baylor College of Medicine in Sept.
A paper by Cristian on a robust protein lysate analysis method has been submitted.
Dr. Rongcai Jiang, M.D., Ph.D., a neurosurgeon from Tianjin, China, joined the lab as a postdoctoral fellow.
Dr. Rudy Guerra, Professor of Statistics at Rice University, is joining the lab this summer as a visiting professor to work on a gene modeling project.
Albert Huang has been accepted to the Graduate School of Biomedical Sciences (GSBS) and joined the lab to work with Drs. Shmulevich and Zhang for his first two rotations.
Drs. Zhang and Shmulevich presented seminars on systems biology and genetic regulatory modeling at the Second TICSP Workshop on Computational Systems Biology held in Helsinki - St. Petersberg, June 14-16, 2004.
A paper by Ramdas et al on long oligo cDNA array has been published by BMC Genomics.
John Dougherty, a graduate student in statistics at Texas A&M, joined the lab to work with Dr. Shmulevich for two months.
Christian Holms joined the lab to work as a volunteer in the summer.
Dr. Zhang has been invited to serve on the Editorial Board of Current Cancer Therapy Reviews
Drs. Zhang and Fuller presented in a Neuro-Oncology conference held in Guangzhou, China during May 21-24, 2004. Our colleague from Canada, Dr. Ab Guha also gave a presentation.
Lynsey Proctor joined the lab as a research assistant.
Dr. Zhang was invited to present at the 19th EuroCell Path Course held in Girona, Spain, May 9-12, 2004.
Dr. Zhang presents at the Molecular Mechanisms in Brain Tumor Course held in Houston, Texas during May 12-16, 2004.
Sarah Dunlap and Jheri Dupart joined our lab to work on their PhD thesis.
Dr. Zhang gave a presentation at the International Conference of Oncology held in Tianjin, China in April 25-27, 2004.
Dr. Zhang's lab is well-represented in March 29th NBC Today Show featuring colon cancer research.
Drs. Shmulevich (PI), Zhang, and Kauffman have received a R21 grant from NIH to study genetic regulatory network during cell differentiation. The two-year funding will start in April.
An new book: Microarray Quality Control, by Drs. Wei Zhang, Ilya Shmulevich, and Jaakko Astola. John Wiley and Sons, Inc. Please see http://www.wiley.com/WileyCDA/WileyTitle/productCd-0471453447.html
Drs. Zhang and Fuller have been invited to serve on the Editorial Board of Neuro-Oncology.
Drs. Zhang and Fuller have been invited to serve on the Editorial Board of Chinese Journal of Clinical Oncology.
Drs. Zhang and Fuller's RO1 on glioma genomics and animal model will be funded from NCI in April.
Drs. Zhang and Shmulevich have been invited to edit the second edition of the book "Computational and Statistical Approaches to Genomics" by Kluwer. The new edition will have 8 new chapters. The book is scheduled to appear by the end of 2004.
Dr. Shmulevich has been invited to present at Japanese Genome Center.
Dr. Zhang has been invited to serve on the Editorial Academy of International Journal of Oncology.
The Core Lab has developed reverse phase protein lysate arrays. Dr. Zhang will give a seminar announcing this new service on January 13th.
First year graduate students Maryam Boseman and Sarah Dunlap joined the lab for their second rotations.
The EXPORT program directed by Dr. Lovell Jones has been funded by NCI/NIH. Drs. Zhang and Regisford are co-directors for a pilot project on genomics.
Dr. Kun-Sang Chang's RO1 has been funded from NCI/NIH. Dr. Zhang and genomics lab will provide support to the promoter array studies.
An new book from Jones and Bartlett: Genomic and Molecular Neuro-Oncology, edited by Drs. Wei Zhang and Gregory Fuller. For detailed information, please see http://bioscience.jbpub.com/catalog/0763722618/
Cristian Mircean joined the lab as a visiting graduate student from Finland.
Sonya Song's paper on IIp45 gene, a novel gene that functions to inhibit invasion, has been published in PNAS.
Harri's paper on breast cancer genomics has been accepted by International Journal of Oncology. Ilya's paper on PBN has been accepted by Comparative and Functional Genomics. Xishan Hao's paper on breast cancer genomics has been accepted in Cancer. The PBN seed network paper has been accepted in Bioinformatics.
Ilya Shmulevich is invited to present a seminar at the Statistics Department of Texas A&M on Oct 9.
Wei Zhang is invited to present a seminar in the Keck Seminar series at Rice University on Oct 10.
Dr. Stuart Kauffman, a pioneer in systems biology and gene regulatory network studies, the author of the seminal book "The Origins of Order: Self-Organization and Selection in Evolution," has been appointed as an Adjunct Professor in the Cancer Genomics Core Lab, Department of Pathology, M. D. Anderson Cancer Center. Dr. Kauffman is working closely with Drs. Ilya Shmulevich and Wei Zhang on several projects addressing genetic regulatory networks.
Shmulevich and Zhang will present at the Pathways, Networks, and Systems: Theory and Experiments conference to be held in Santorini, Greece from September 28 - October 2, 2003.
Ying Zhao joined the lab as a part-time research investigator.
Antti Niemisto, an imaging graduate student from Finland, has joined the lab to work with Dr. Shmulevich for 6 months.
A new graduate student, Jheri Dupart, joined the lab for a 10-week rotation.
A new paper on colon cancer genomics has been accepted for publication in the Sept issue of Cancer Biology and Therapy. Check the journal web site for abstract.
A new paper on pathway analysis of lymphoma has been accepted for publication in International Journal of Oncology.
Ilya Shmulevich's paper on genetic regulatory network is published in PNAS 100:10734-10739.
Albert Huang, after a very successful summer, is going back to school in California.
Weiping Shen, after working in the lab for three years, will pursue a new career in biotech industry. Shouming Kong, after working in the lab for 2.5 years, will go back to school next month. We wish them the best of luck in their new careers.
A new graduate student in MD/Ph.D program, George Wang, has joined the lab for his PhD thesis program. Welcome!
Hua Wang's paper on IGFBP2 function in cell invasion has been published in Cancer Res as an Advances in Brief in August 1 issue.
Hua Wang's big day: PhD defense on July 30th. It was SUCCESSFUL. Congratulations! Hua will continue as a postdoctoral fellow.
New postdoc Dr. Eun Ju Lee from Samsung Medical Center joined the lab.
The CCSG directed by Dr. Mendelsohn has been funded. Genomics Core directed by Drs. Hamilton, Lozano, and Zhang is part of the CCSG.
Drs. Wei Zhang and Raph Pollock have received an RO1 from NCI/NIH to study sarcoma genomics. Funding begins in July, 2003.
Graduate student Matt McDonald presented a poster on oligodendroglioma at 2003 AACR.
Valentina Agnese, a visiting student from Italy, joins the lab working on a colon project with Drs. Hamilton and Zhang.
Research Associate Sonya Song received an institutional grant to study glioma invasion signal transduction pathways.
Drs. Shmulevich, Fuller, and Zhang presented talks on gene regulatory network, tissue microarray, and cancer genomics at the Cancer Genomics/Systems Biology Workshop held at Tampere, Finland in June.
Albert Huang joined the lab for the summer.
Graduate student Hua Wang has received The Bristol-Myers Squibb Award in Clinical/Translational Research at M.D. Anderson Trainee Recognition event in May.
Graduate student Hua Wang has received a Travel Award from Graduate School to present a poster at the annual conference of the US Canadian Academy of Pathologists, March 22-28, Washington DC.
Visiting graduate student Harri Lahdesmaki is heading home after a highly successful stay in the Genomics Lab. During the last six months, Harri participated in writing six manuscripts--a record hard to beat.
Ilya Shmulevich is presenting a talk at the Toxicogenomics conference held in Salt Lake city, Utah, March 10-12.
A new paper in press in Nucleic Acid Res by Shmulevich, Astola, Cogdell, Hamilton and Zhang.
The Core Lab presented four posters at the 2003 Oncogenomics conference, Jan 28-Feb2. Visiting graduate student Harri Lahdesmaki won an AACR Scholar-in-Training Award to present a poster on breast cancer genomics. This is a joint project between our group with Dr. Xishan Hao's group from Tianjin Cancer Hospital.
Dr. Stuart A. Kauffman, M.D.,External Professor, Santa Fe Institute,Prof. Emeritus, University of Pennsylvania, Chief Scientist, Bios Group, came to visit and presented a seminar entitled "Biased Gene Control Rules Suggest Genetic Regulatory Networks are in an Ordered Regimeon " on Jan 15. Dr. Kauffman is a theoretical biologist, is a leader in complexity
theory, applied molecular evolution, origins of life, and developmental
genetics. He is the author of "The Origins of Order: Self-Organization
and Selection in Evolution", "At Home in the Universe: The Search for
the Laws of Self-Organization and Complexity", and "Investigations", all
by Oxford University Press.
Seven abstracts from Drs. Zhang and Fuller's group have been accepted by the 2003 USCAP conference to be held in DC. Among them, Dr. Fuller will give a platform presentation on glioma genomics study. Dr. Huamin Wang will also give a platform presentation on high throughput marker studies. Other studies include the breast cancer genomics project, a collaboration project with Dr. Xishan Hao from Tianjin Cancer Hospital in China.
Dr. Toru Kobayashi gave a platform presentation of the lymphoma genomics study at the American Society of Hematology annual meeting held in Philadelphia in December 2002.
Graduate student Matt McDonald presented a poster at the Society of Neuro-Oncology annual conference held in San Diego, Nov 22, 2002.
Drs. Xishan Hao, Stanley Hamilton, Wei Zhang co-chaired an International Conference on Translational Cancer Research and Therapy, October 21-23, 2002, Tianjin, P.R. China. See http://www.tijmu.edu.cn/ictcrt for detailed information and registration material. Drs. Hamilton, Zhang, Fuller, and Shmulevich presented at the conference. Other invited speakers from the US were Drs. W. Cavenee, A. Deisseroth, and J. Schnitzer.
Drs. Wei Zhang, Gregory Fuller, Ilya Shmulevich, and Webster Cavenee were invited to present at the Medicine in the 21st Century conference held in Shanghai, China, Oct 25-29.
Drs. Zhang and Shmulevich are invited to serve as judges for abstracts submitted to the Annual Biomedical Research Conference for Minority Students (ABRCMS) to be held in New Orleans in November this year.
Dr. Francis Collins, the Director of Human Genome Project and the Director of NHGRI visited the Core Lab on September 17th, 2002.
Drs. Wei Zhang and Gregory Fuller are editing a book on Genomic and Molecular Neuro-Oncology to be published early in 2003. Dr. Ilya Shmulevich is writing a book on PBN to be published in 2003.
New papers accepted or published: (1) Kobayashi T, Yamaguchi M, Kim S, Morikawa J, Ogawa S, Ueno S, Suh E, Dougherty E, Shmulevich I, Shiku H, and Zhang W. Microarray reveals differences in both tumor and vascular specific gene expression in de novo CD5+ and CD5- diffuse large B-cell lymphomas. Cancer Res. 2003 (2)
Kim S, Dougherty ER, Shmulevich I, Hess KR, Hamilton SR, Trent JM, Fuller GN, and Zhang W. Identification of combination gene sets for glioma classification. Mol. Cancer Therapeutics 2002; (3) Lee SH, Kim J-W, Lee, HW, Cho Y, Oh S, Jung C, Zhang W, Lee JH. Interferon regulatory factor-1 (IRF-1) is a mediator for interferon-g induced attenuation of telomerase Activity and human telomerase reverse transcriptase (hTERT) expression. Oncogene 2003; (4) Wang J, Hu L, Hamilton SR, Coombes KR, and Zhang W. Evaluating the performance of two RNA amplification strategies for cDNA microarray experiments. Biotechnique (in press).
Dr. Baochong Chang, a fellow in the Division of Cancer Medicine, Dr. Jae Soo Koh, a sarcoma pathologist from Korean Cancer Hospital, joined the lab to work on genomic projects (August 2002)