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M.D.
Anderson's Cytogenetic Technology Program
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The Program is a six-month, highly intensive
course of study in preparation for national certification
as a cytogenetic technologist. For each course you will
receive classroom lectures, laboratory demonstrations, and
technical experience.
Because UTMDACC is one of the largest cancer centers in
the world, many special areas of instruction can be presented,
such as multiplex FISH, microdissection of chromosomes,
and comparative genomic hybridization.
The following are the topics included in the curriculum:
Medical Genetics
Clinical Cytogenetics
Laboratory Operations
Prenatal Cytogenetics
Cytogenetics of Hematological Malignancies
Cytogenetics of Solid Tumors and Environmental Mutagens
Special Topics:
Molecular Diagnostics
Cytogenetic Journal Club
Emerging Technologies
Student Research Project
Upon successful completion of our Program you will be awarded
a Certificate of Completion and will be eligible to take
the national certification exams.
Student Activities
Function: Performs procedures using analytical methodology
in a clinical cytogenetic laboratory under the direct supervision
of an experienced and certified cytogenetic technologist.
Classroom instruction and demonstration of competency precede
hands-on activities. Students must complete each course
with a minimum grade of 70% to remain in the Program.
Under direct supervision of certified cytogenetic
technologists, the students set up cultures for chromosome
analysis on peripheral blood, bone marrow, amniotic fluid,
and tissue specimens. Techniques for harvesting and preparing
slides from these various cultures are described in detail
and students gain hands-on experience. Students do not work
with material that is used for patient reporting.
The students learn the specialized staining techniques required
to differentiate special regions of human chromosomes and
to induce specific banding patterns necessary for the identification
of genetic changes. These include but are not limited to GTG
Banding, QFQ Banding, RFA banding, and CBG banding techniques.
Students are instructed in the methodology required to scan,
review, count cells and analyze slides for metaphase spreads.
Detailed instructions in imaging of cytogenetic preparations
both with conventional photography and darkroom techniques
as well as with automated computer imaging systems are included
in the curriculum.
Students spend a significant portion of the course mastering
the pattern recognition necessary for accurate identification
of the normal human chromosomes banding pattern utilizing
the GTG banding technique. Students become familiar with common
abnormal banding patterns associated with genetic disease.
DNA probe methodology is an important part of the curriculum
and students become proficient in labeling of DNA with fluorescent
dyes and hybridization of DNA to target DNA both on agarose
gels and glass microscope slides. Techniques learned included
Southern blot analysis, PCR methodology, and Fluorescent in
situ hybridization.
Why M.D. Anderson?
In a recent nationwide survey published in U.S. News and World
Report, M.D. Anderson was named number two in the nation in
cancer care. One of the models for federally designated comprehensive
cancer centers, this 425 bed Hospital is internationally recognized
for its exceptional strength in patient care, research, and
educational programs.
The UTMDACC laboratories offer a unique educational experience
not found in many institutions. Over three million tests are
performed annually on patients who travel to M.D. Anderson
from all parts of the United States and abroad. Thus, your
education will include the entire spectrum of laboratory testing,
from the relatively uncomplicated to the highly specialized
procedures only available at a tertiary care center such as
M.D. Anderson.
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