Program Goals & Objectives
The goal of the Medical Oncology fellowship program
is to train oncologists for academically oriented careers. The program
is designed to incorporate training in the diagnosis and management
of a broad spectrum of neoplastic diseases.
At the end of two years of training, each fellow
is expected to be familiar with the natural history of the major
and common human malignancies and to be knowledgeable about appropriate
diagnostic and therapeutic approaches. By then, each fellow will
have had exposure to a variety of research programs and will be
expected to have demonstrated his/her ability to complete an independent
research project in the laboratory or clinic.
At the end of a third year of training, the fellow
is expected to be competent, skilled oncologist able to assume a
position as an independent investigator in either a laboratory-based
or clinically oriented research program. Fellows who complete the
training should be proficient in the following procedures: serial
measurement of palpable tumor masses, bone marrow aspiration and
biopsy, administration of chemotherapeutic agents and biological
response modifiers through all therapeutic routes, and management
and care of indwelling venous access catheters.
First Year
During the first year, each fellow is assigned two
or three two-month rotations and six one-month rotations. These
include rotations in both solid tumors and hematologic malignancies.
On those services such as acute leukemia and bone marrow transplantation,
where the primary activity is inpatient care, the fellow coordinates
care for hospitalized patients. On other services (lymphoma and
solid tumors) the fellow's primary assignment is in the clinic.
Under the supervision of an attending physician, the fellow attends
outpatients referred to the institution and a small number of inpatients.
The fellow also is involved in the clinical research program for
each service or section and is encouraged to develop a research
program of his own.
A typical first year of training consists of three
two-month rotations on the hematology services (i.e., leukemia,
lymphoma/myeloma, bone marrow transplantation) and six one-month
rotations on solid tumor services (i.e., melanoma/sarcoma, breast,
genitourinary, thoracic/head and neck, gastrointestinal and gynecological
medical oncology).
Upon fellows' completion of the first year of study,
Division of Medicine faculty selects by ballot one outstanding fellow
to receive the Clifton D. Howe Award for Clinical Excellence.
Second and Third Years
During the second and third years, a fellow may
choose to devote his/her training to either a clinical or laboratory
based research project. The fellow's project is supervised by an
experienced faculty member who serves as a mentor. Projects are
reviewed by a committee of advisors on a regular basis, and a formal
report is presented annually. The advisors assess the project, evaluate
the fellow's methods and findings, and provide advice.
Clinician-Investigator The clinician-investigator
program provides an opportunity to understand new drug development
and evaluation in depth as well as to understand the phonotypic
heterogeneity of human cancer. Emphasis will be placed not only
on protocol design, protocol implementation and biostatistics, but
also on the biology of human cancer. One or more protocols will
be developed in collaboration with a faculty mentor. Didactic course
work can be completed at the U.T. Graduate School of Biological
Science at the School of Public Health. Externships of 2-12 weeks
will be conducted at government agencies and in private sector companies
for fellows to better understand different perspectives on drug
development. From these experiences, a fellow on the clinician-investigator
tract should better understand how drugs are chosen for development,
the time frame for pre-clinical and clinical evaluation, the impact
of market analysis, regulatory policies and procedures, and the
role of the NCI in facilitating discovery, scale up and evaluation
of new drugs.
Physician-Scientist The physician-scientist
program permits fellows to work in the laboratory for two years
under the direction of one of our mentors. Fellows who excel during
this interval will be eligible to compete for the junior faculty
physician scientist awards that have recently been established at
M.D. Anderson and that permits 80% protected time for an additional
3-5 years for faculty at the Assistant Professor level. Consequently,
come 5-7 years of support could be made available for a young investigator
to develop the expertise, credibility and publication record to
complete successfully for peer reviewed funding. This interval would
permit formal course work and the completion of requirements for
a Ph.D. degree in the U.T. Graduate School of Biological Sciences.
Over the last 10 years two Medical Oncology fellows have completed
fellowship training in oncology while pursuing a Ph.D. Both have
joined the M.D. Anderson faculty. The laboratory projects of fellows
will be reviewed semi-annually by a "thesis" committee that will
include the fellow's mentor and at least two other knowledgeable
faculty members.
Community-Based Research/M.P.H.
The community-based research program will take advantage
of our institution's extensive program in cancer control research
and chemoprevention. Each fellow will complete two projects with
mentors in the program. In addition there will be the option to
obtain an M.P.H. degree at The University of Texas School of Public
Health during this two year period. The Executive Committee evaluates
the training of all fellows and oversees research progress during
the last two years. Second and third year fellows meet periodically
with Drs. Bast and Pazdur. Projects are presented annually with
the entire group of fellows and mentor in attendance.
Bioimmunotherapy The goal of
this training program is to provide a curriculum that will lead
to the development of independent clinician/scientists capable of
translating new advances in basic immunobiology into the clinical
area. Candidates that have these goals will be accepted into the
program. The Bioimmunotherapy training program provides exposure
to a broad range of topics including biostatistics, clinical trial
design, genetics, cell biology, immunobiology, molecular biology
and biochemistry. Through the Graduate School of Biomedical Sciences,
fellows will have access to structured courses in different disciplines,
which will be recommended by the sponsoring committee on an individual
basis.
Continuity Clinic For the duration
of the training, a fellow must participate in at least one continuity
clinic per week (for at least one half-day) either at M. D. Anderson
Cancer Center or L. B. Johnson Harris County Hospital where the
fellow sees at least one new patient per week and establishes his/her
own patient base to be seen in follow-up visits. Six to eight patients
per week are seen in follow up visits. The
clinic and/or attending physician with whom the fellow works in
the continuity setting is chosen by the fellow with the approval
of the program director. The recommended choice should integrate
the individual fellow's career objectives with the fellowship program's
goals. A fellow may elect to participate in more than one continuity
clinic.
Scientific Writing In addition
to meeting American Board of Internal Medicine requirements, M.
D. Anderson Cancer Center expects all of its medical oncology/hematology
fellows to complete a manuscript suitable for publication before
graduation from the program. This requirement is met when a fellow
authors a manuscript that is published or in press in a scientific
journal (preferably peer-reviewed) or textbook. To prepare fellows
to meet the goal of scholarly writing, the program offers:
- small classes on the subject of scientific writing
- on-going support of scientific editors and faculty co-authors
- lecture series on biostatistics and their applications
In 1993, the program's scientific writing support
efforts culminated in the publication of a comprehensive medical
oncology textbook whose chapters were exclusively first-authored
by M. D. Anderson's medical oncology/hematology fellows. Based on
customer demand and requests by the publisher for subsequent editions,
this project has become a permanent part of the fellowship program.
Courses & Lectures Each fellow
is expected to attend weekly conferences and lectures specifically
scheduled for fellows, i.e., weekly clinical case presentations,
core lectures, chiefs; rounds, expanded medical grand rounds, biostatistics,
communication skills, and journal club. First-year fellows are expected
to attend Morning Report with the medical housestaff. Fellows are
encouraged to attend lectures sponsored by the departments and divisions
of the institution.
Options With the approval of
the program director, fellows fellows may choose to pursue concurrently
with their fellowship:
- a Master of Public Health (M.P.H.) degree at
The University of Texas School of Public Health; or
- a Ph.D. degree at The University of Texas Graduate
School of Biomedical Sciences
Additionally, qualified fellows who have the fellowship
program director's approval may enter M. D. Anderson's Physician-Scientist
Postdoctoral Program. Physicians entering this program can expect
an increased stipend and a faculty associate appointment. The purpose
of this program is for physician scientists, through an fourth and
fifth year of training, to prepare for full participation on the
faculty and to obtain peer-reviewed funding. Fellows accepted into
this program are expected to take courses in such topics as ethics,
biostatistics, grant writing and molecular studies. Publications
and presentations at national and international meetings are expected
at this level of training.
Accreditation
The University of Texas M. D. Anderson Cancer Center
Medical Oncology Fellowship program is approved by the Accreditation
Council for Graduate Medical Education. Fellows who successfully
complete this three-year training program are eligible to sit for
the American Board of Internal Medicine (ABIM) Certifying Examination
in the subspecialty of Medical Oncology. If, during their three-year
training, fellows elect to complete proscribed rotations in classical
Hematology at either The University of Texas Medical School at Houston
or at the Baylor College of Medicine, they will be eligible to sit
for the ABIM certifying examinations in the dual subspecialties
of Hematology and Medical Oncology.
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