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Reversible MR changes with Cyclosporine A
Cyclosporine A induced neurotoxicity: Neurotoxicity is a well-described complication of Cyclosporine A (CsA) therapy. This drug is commonly given to organ transplant patients and leukemics undergoing BMT. The clinical syndrome consists of seizures, cortical blindness, speech and motor disturbances, and alterations in consciousness, typically within the first month of therapy. Imaging findings include T2 hyperintensity on MRI, typically in a parieto-occipital distribution (case 27). With discontinuation of CsA, the symptoms and radiologic changes are reversible (case 27).
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©2002
The Levit Radiologic - Pathologic Institute
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Last updated; February 2002 - contact Webmaster |
©2002
The University of Texas M. D. Anderson Cancer Center
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