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1999 Publications

Adenovirus-Mediated p53 Gene Transfer in Advanced Non-Small-Cell Lung Cancer

Journal of the National Cancer Institute, Vol. 91, No. 9, 763-771, May 5, 1999

Stephen G. Swisher, Jack A. Roth, John Nemunaitis, David D. Lawrence, Bonnie L. Kemp, Cesar H. Carrasco, Dee G. Connors, Adel K. El-Naggar, Frank Fossella, Bonnie S. Glisson, Waun K. Hong, Fadlo R. Khuri, Jonathan M. Kurie, Jack J. Lee, Jin S. Lee, Michael Mack, James A. Merritt, Dao M. Nguyen, Jonathan C. Nesbitt, Roman Perez-Soler, Katherine M. W. Pisters, Joe B. Putnam, Jr., William R. Richli, Michael Savin, David S. Schrump, Dong M. Shin, Allan Shulkin, Garrett L. Walsh, Juliette Wait, David Weill, M. Kimberly A. Waugh

New Nasal Gene Therapy Found Effective in Treatment of Osteosarcoma Metastases to Lungs

Joining Dr. Worth on the study were Drs. Eugenie Kleinerman, Shu-Fang Jia and Z.C. Zhou of M. D. Anderson.

Chemotherapy immediately, following autologous stem cell transplantation in patients with advanced breast cancer

Clin. Can. Res. 4:2717-2721. Blood 92:672-682.

Rahman, Z., Kavanagh, J., Champlin, R., Giles, R., Hanania, E., Fu, S., Zifei, Zu., Rakesh, M., Holmes, R., Kudelka, A., Claxton, D., Verschraegen, C., Gajewski, J., Andreeff, M., Heimfeld, S., Berenson, R., Ellerson, D., Calvert, L., Mechetner, E., Holzmayer, T., Dayne, A., Hamer, J., Bachier, C., Ostrove, J., Przepiorka, D., Burtness, B., Cote, R., Bast, R., Hortobagyi, G., and Deisseroth, A. (1998). .

Genetic Therapy of Solid Tumor and Hematopoietic Neoplasms

Vol. II, Progress in Anti-Cancer Chemotherapy, pp. 96-105, eds.

Hortobagyi, G. and Khayat, Blackwell Science, Inc.

Nankorn, T., Fu, S., Yin, L. H., Rahman, Z., Kavanagh, J., Fugii, T., Chung, I., Yap, R., Giles, R., Pizzorno, G., and Deisseroth, A. (1999).

An agent that increases tumor suppressor transgene product coupled with systemic transgene delivery inhibits growth of metastatic lung cancer in vivo

Cancer Res (Adv. Brf.) 58: 4761-4765, 1998

Mafumi Kataoka, Guido Schumacher, Richard J. Cristiano, E. Neely Atkinson, Jack A. Roth, and Mukhopadhyay T.

Hematopoietic retroviral gene marking in patients with follicular non-Hodgkin’s lymphoma.

Leuk Lymphoma 32:279-288, 1999.

Bachier CR, Giles RE, Ellerson D, Hanania EG, Garcia-Sanchez F, Andreeff M, Cabanillas F, Champlin R, Choudhury R, Berenson R, Heimfeld S, Deisseroth AB:

Overexpressed WAF1/Cip1 renders glioblastoma cells resistant to chemotherapy agents 1,3-bis (2-chloroethyl)-1-nitrosourea and cisplatin

Cancer Res 58:1538-1543, 1998.

Ruan S, Okcu MF, Ren JP, Chiao P, Andreeff M, Levin V, Zhang W.

Overexpression of Bax gene sensitizes K562 erythroleukemia cells to apoptosis induced by selective chemotherapeutic agents

Oncogene 16:1587-1591, 1998.

Kobayashi T, Ruan S, Clodi K, Kliche K-O, Shiku H, Andreeff M, Zhang W.

Retrovirus-mediated wild-type p53 gene transfer to tumors of patients with lung cancer

Nature Medicine 2(9):985-991, 1996.

Roth JA, Nguyen D, Lawrence DD, Kemp BL, Carrasco CH, Ferson DZ, Hong WK, Komaki R, Lee JJ, Nesbitt JC, Pisters KMW, Putnam JB, Schea R, Shin DM, Walsh GL, Dolormente MM, Han C-I, Martin FD, Yen N, Xu K, Stephens LC, McDonnell TJ, Mukhopadhyay T, Cai D.

Gene therapy for lung cancer injection of wild p53 gene by retrovirus vector.

Experimental Medicine 15:251-253, 1997.

Kataoka M, Komaki R, Roth JA.

Expression of Apoptosis-related Genes in Human Head and Neck Squamous Cell Carcinomas Undergoing p53-mediated Programmed Cell Death

Clin. Can. Res. 5:361-369, 1999

Frederick, M., Holton, P., Hudson, M., Wang, M., and Clayman, G.

Combination E2F-1 and p53 Gene Transfer Does Not Enhance Growth Inhibition in Human Squamous Cell Carcinoma of the Head and Neck

Clin. Can. Res. 4:2265-2272, 1998

Frank, D., Liu, T., Frederick M., and Clayman G.

Bystander Effect in the Adenovirus-mediated Wild-Type p53 Gene Therapy Model of Human Squamous Cell Carcinoma of the Head and Neck

Clin. Can. Res. 4:2521-2527, 1998

Frank, D., Frederick, M., Liu, T., and Clayman, G.

Adenovirus-Mediated P53 Gene Transfer in Patients With Advanced Recurrent Head and Neck Squamous Cell Carcinoma

Journal of Clinical Oncology 16(6):2221-2232, 1998

Clayman, G., El-Naggar, A., Lippman, S., Henderson, Y., Frederick, M., Merritt, J., Zumstein, L., Timmons, T., Liu, T., Ginsberg, L., Roth, J., Hong, W., Bruso, P., and Goepfert, H.

In Vitro Growth Suppression by Adenoviral Transduction of p21 and p16 in Squamous Cell Carcinoma of the Head and Neck

Arch Otoloryngol Head Neck Surgery 124:88-92, 1998

Mobley, S., Liu, T., Hudson, M., and Clayman, G.

Antiangiogenesis Treatment for Gliomas: Transfer of Antisense-Vascular Endothelial Growth Factor Inhibits Tumor Growth in Vivo

Cancer Res 59:895-900, 1999

Im, S., Gomez-Manzano, C., Fueyo, J., Liu, T., Ke, L., Kim, J., Lee, H., Steck, P., Kyritsis, A., and Yung, W.

Overexpression of E2F-1 in glioma triggers apoptosis and suppresses tumor growth in vitro and in vivo

Nature Medicine 4(6):685-690, 1998

Fueyo, J., Gomez-Manzano, C., Yung, W., Liu, T., Alemany, R., McDonnell, T., Shi, X., Rao, J., Levin, V., and Kyritsis, A.

Suppression of human glioma growth by adenovirus-mediated Rb gene transfer

Neurology 50(5):1307-15, 1998

Fueyo, J., Gomez-Manzano, C., Yung, W., Liu, T., Alemany, R., Bruner, J., Chintala, S., Rao, J., Levin, V., and Kyritsis, A.

Adenovirus-mediated p16 transfer to glioma cells induces G1 arrest and protects from paclitaxel and topotecan: implications for therapy

International Journal of Oncology 12:665-669, 1998

Fueyo, J., Gomez-Manzano, C., Puduvalli, V., Martin-Duque, P., Perez-Soler, R., Levin, V., Yung, W., and Kyritsis, A.

Transforming growth factor-alpha antisense vectors can inhibit glioma cell growth

Journal of Neuro-Oncology 43(2):127-35, 1999

Tang, P., Jasser, S., Sung, J., Shi, Y., Steck, P., and Yung W.

Bcr: a negative regulator of the Bcr-Abl oncoprotein

Oncogene 18(31):4416-4424, 1999

Wu, Y., Ma, G., Lu, D., Lin, F., Xu, H., Liu, J., and Arlinghouse, R.

Adenovirus-mediated Wild-type p53 gene transfer as a surgical adjuvant in advanced head and neck cancers

Clin. Can. Res. 5(7):1715-22, 1999

Clayman, G., Frank, D., Bruso, P., and Goepfert, H.,