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2001 Publications

Modulation of nucleotide excision repair capacity by XPD polymorphisms in lung cancer patients
Spitz, M.R., Wu, X., Wang, Y., Wang, L.E., Shete, S., Amos, C.I., Guo, Z., Lei, L., Mohrenweiser, H., and Wei, Q.
Cancer Res., 61:1354-1357, 2001.

Age-associated risk of cancer among individuals with N-acetyltransferase 2 (NAT2) mutations and mutations in DNA mismatch repair genes
Frazier, M.L., O'Donnell, F.T., Kong, S., Gu, X., Campos, I., Luthra, R., Lynch, P.M., and Amos, C.I.
Cancer Res., 61:1269-1271, 2001.

Genetic linkage methods for quantitative traits
Amos, C.I., and de Andrade M.
Stat. Methods Med. Res., 10:3-25, 2001.

Cyclin D1 polymorphisms and increased risk of colorectal cancer at young age
Kong, S., Wei, Q., Amos, C.I., Lynch, P.M., Levin, B., Zong, J., and Frazier, M.L.
J. Natl. Cancer Inst., 93:1106-1108, 2001.
The association of microsomal epoxide hydrolase polymorphisms and lung cancer risk in African-Americans and Mexican-Americans
Wu, X., Gwyn, K., Amos, C.I., Makan, N., Hong, W.K., and Spitz, M.R.
Carcinogenesis, 22:923-928, 2001.
Cytokine-regulated expression of survivin in myeloid leukemia
Carter, B.Z., Milella, M., Altieri, D.C., and Andreeff, M.
Blood, 97:2784-2790, 2001.
Expression of apoptosis proteins in chronic myelogenous leukemia: associations and significance
Ravandi, F., Kantarjian, H.M., Talpaz, M., O'Brien, S., Faderl, S., Giles, F.J., Thomas, D., Cortes, J., Andreeff, M., Estrov, Z., Rios, M.B., and Albitar, M.
Cancer 91:1964-1972, 2001.
BCR gene expression blocks Bcr-Abl induced pathogenicity in a mouse model
Lin, F., Monaco, G., Sun, T., Liu, J., Lin, H., Stephens, C., Belmont, J., and Arlinghaus, R.B.
Oncogne, 20:1873-1881, 2001.
Expression of a truncated first exon BCR sequence in chronic myelogenous leukemia cells blocks cell growth and induces cell death
Wang, Y., Liu, J., Wu, Y., Luo, W., Lin, S.H., Lin, H., Hawk, N., Sun, T., Guo, J.Q., Estrov, Z., Talpaz, M., Champlin, R. and Arlinghaus R.B.
Cancer Res., 61:138-144, 2001.
Preparation and application of antibodies to phosphoamino acid sequences
Sun, T., Campbell, M., Gordon, W., and Arlinghaus, R.B.
Biopolymers, 60:61-75, 2001.
Expression of bcr-abl mRNA in individual chronic myelogenous leukemia cells as determined by in situ amplification
Pachmann, K., Zhao, S., Schenk, T., Kantarjian, H., El-Naggar, A.K., Siciliano, M.J., Guo, J.Q., Arlinghaus, R.B., and Andreeff, M.
Br. J. Haematology, 112:749-759, 2001.
p73 gene alterations and expression in primary oral and laryngeal squamous carcinomas
El-Naggar, A.K., Lai, S., Clayman, G.L., Mims, B., Lippman, S.M., Coombes, M., Luna, M.A., Lozano, G.
Carcinogenesis, 22:729-735, 2001.
Epidermal growth factor receptor-targeted therapy with C225 and cisplatin in patients with head and neck cancer
Shin, D.M., Donato, N.J., Perez-Soler, R., Shin, H.J., Wu, J.Y., Zhang, P., Lawhorn, K., Khuri, F.R., Glisson, B.S., Myers, J., Clayman, G., Pfister, D., Falcey, J., Waksal, H., Mendelsohn J., and Hong, W.K.
Clin. Cancer Res., 7:1204-1213, 2001.
SCCA1 expression in T-lymphocytes peripheral to cancer cells is associated with the elevation of serum SCC antigen in squamous cell carcinoma of the tongue
Yasumatsu, R., Nakashima, T., Azuma, K., Hirakawa, N., Kuratomi, Y., Tomita, K., Cataltepe, S., Silverman, G.A., Clayman, G.L., and Komiyama, S.
Cancer Lett., 167:205-213, 2001.
Expression of protease-activated receptor 1 in oral squamous cell carcinoma
Liu, Y., Gilcrease, M.Z., Henderson, Y., Yuan, X.H., Clayman, G.L., and Chen, Z.
Cancer Lett., 169:173-180, 2001.
All-trans-retinoic acid enhances the effect of adenovirus-mediated wild-type p53 gene transfer in head and neck squamous cell carcinoma
Nakashima, T., Sun, S.Y., Lotan, R., Fujiwara, T., Yasumatsu, R., Komiyama, S., and Clayman, G.L.
Laryngoscope, 111:1459-1464, 2001.
Connexin 26 enhances the bystander effect in HSVtk/GCV gene therapy for human bladder cancer by adenovirus/PLL/DNA gene delivery
Tanaka, M., Frazier, G.C., De La Cerda, J., Cristiano, R.J., Liebert, M., and Grossman, H.B.
Gene Ther., 8:139-148, 2001.
Augmenting transgene expression from carcinoembryonic antigen (CEA) promoter via a GAL4 gene regulatory system
Koch, P.E., Guo, Z.S., Kagawa, S., Gu, J., Roth, J.A., and Fang, B.
Molecular Ther., 3:278-283, 2001.
Deficiency of caspase-3 in MCF7 cell blocks Bax-mediated nuclear fragmentation but not cell death
Kagawa, S., Gu, J., Honda, T., McDonnell, T.J., Swisher, S.G., Roth, J.A., and Fang, B.
Clin. Cancer Res., 7:1474-1480, 2001.

Adenoviral-mediated bax overexpression for the induction of therapeutic apoptosis in prostate cancer
Li, X., Marani, M., Yu, J., He, Z., Fang, B., Roth, J.A., Denner, L., and Marcelli, M.
Cancer Res., 61:186-191, 2001.

Effects of N-(4-hydroxyphenyl)retinamide on hTERT expression in the bronchial epithelium of cigarette smokers
Soria, J.C., Moon, C., Wang, L. Hittelman, W.N., Jang, S.J., Sun, S.Y., Lee, J.J., Liu, D., Kurie, J.M., Morice, R.C., Lee, J.S., Hong, W.K., and Mao, L.
J. Natl. Cancer Inst., 93:1257-1265, 2001.
Loss of Fhit expression is a predictor of poor outcome in tongue cancer
Lee, J.I., Soria, J.C., Hassan, K., Liu, D., Tang, X., El-Naggar, A., Hong, W.K., and Mao, L.
Cancer Res., 61:837-841, 2001.
Increased reinoic acid responsiveness in lung carcinoma cells that are nonresponsive despite the presence of endogenous retinoic acid receptor (RAR) beta by expression of exogenous retinoid receptors retinoid X receptor alpha, RAR alpha, and RAR gamma
Wan, H., Hong, W.K., and Lotan, R.
Cancer Res., 61:556-564, 2001.
Sensitivity to DNA damage induced by benzo(a)pyrene diol epoxide and risk of lung cancer: a case-control analysis
Li, D., Firozi, P.F., Wang, L.E., Bosken, C.H., Spitz, M.R., Hong, W.K., and Wei, Q.
Cancer Res., 61:1445-1450, 2001.
Cyclooxygenase-2 overexpression is a marker of poor prognosis in stage I non-small cell lung cancer
Khuri, F.R., Wu, H., Lee, J.J., Kemp, B.L., Lotan, R., Lippman, S.M., Feng. L., Hong, W.K., and Xu, X.C.
Clin. Cancer Res., 7:861-867, 2001.
Modulation of proliferating cell nuclear antigen in the bronchial epithelium of smokers
Khuri, F.R., Lee, J.S., Lippman, S.M., Lee, J.J., Kalapurakal, S., Yu, R., Ro, J.Y., Morice, R.C., Hong, W.K., and Hittelman, W.N.
Cancer Epidemiol. Biomarkers Prev., 10:311-318, 2001.
Chromosome polysomy and histological characteristics in oral premalignant lesions
Kim, J., Shin, D.M., El-Naggar, A., Lee, J.S., Corrales, C., Lippman, S.M., Hong, W.K., and Hittelman, W.N.
Cancer Epidemiol. Biomarkers Prev., 10:319-325, 2001.
Polymorphisms of methylene-tetrahydrofolate reductase and risk of lung cancer: a case-control study
Shen, H., Spitz, M.R., Wang, L.E., Hong, W.K., and Wei, Q.
Cancer Epidemiol. Biomarkers Prev., 10:397-401, 2001.
Identification of retinamides that are more potent than N-4(4-hydroxyphenyl)retinamide in inhibiting growth and inducing apoptosis of human head and neck and lung cancer cells
Sun, S.Y., Yue, P., Kelloff, G.J., Steele, V.E., Lippman, S.M., Hong, W.K., and Lotan, R.
Cancer Epidemiol. Biomarkers Prev., 10:595-601, 2001.
p53 protein accumulation and genomic instability in head and neck multistep tumorigenesis
Shin, D.M., Charuruks, N., Lippman, S.M., Lee, J.J., Ro, J.Y., Hong, W.K., and Hittelman, W.N.
Cancer Epidemiol. Biomarkers Prev., 10:603-609, 2001.
In vitro BPDE-induced DNA adducts in peripheral lymphocytes as a risk factor for squamous cell carcinoma of the head and neck
Li, D., Firozi, P.F.Chang, P., Wang, L.E., Xiong, P., Sturgis, E.M., Eicher, S.A., Spitz, M.R., Hong, W.K., and Wei, Q.
Int. J. Cancer, 93:436-440, 2001.
Clinical significance of cyclin b1 protein expression in squamous cell carcinoma of the tongue
Hassa, K.A., El-Naggar, A.K., Soria, J.C., Liu, D., Hong, W.K., and Mao, L.
Clin. Cancer Res., 7:2458-2462, 2001.
Synergistic inhibition of human lung cancer cell growth by adenovirus-mediated wild-type p53 gene transfer in combination with docetaxel and radiation therapeutics in vitro and in vivo
Nishizaki, M., Meyn, R.E., Levy, L.B., Atkinson, E.N., White, R.A., Roth, J.A., and Ji, L.
Clin. Cancer Res., 7:2887-2897, 2001.
Interleukin (IL)-12 and IL-12 gene transfer up-regulate Fas expression in human osteosarcoma and breast cancer cells
Lafleur, E.A., Jia, S.-F., Worth, L.L., Zhou, Z., Owen-Schaub, L.B., and Kleinerman, E.S.
Cancer Res., 61:4066-4071, 2001.
E1A sensitizes HER2/neu-overexpressing Ewing's sarcoma cells to topoisomerase II-targeting anticancer drugs
Zhou, Z., Jia,S.-F., Hung, M.C., and Kleinerman, E.S.
Cancer Res., 61:3394-3398, 2001.
Mylotarg (gymtuzumab ozogamicin) therapy is associated with hepatic venoocclusive disease in patients who have not received stem cell transplantation
Giles, F.J., Kantajian, H.M., Kornblau, S.M., Thomas, D.A., Garcia-Manero, G., Waddelow, T.A., David, C.L., Phan, A.T., Colburn, D.R., Rashid, A., and Estey, E.H.
Cancer, 92:406-413, 2001.
Preemptive control of graft-versus-host disease in a murine allogeneic transplant model using retrovirally transduced murine suicidal lymphocytes
Kornblau, S.M., Stiouf, I., Snell, V., Przepiorka, D., Stevens, L.C., Champlin, R., and Marini, 3rd, F.C.
Cancer Res., 61:3355-3360, 2001.
Therapeutic targeting of the MEK/MAPK signal transduction module in acute myeloid leukemia
Milella, M., Kornblau, S.M., Estrov, Z., Carter, B.Z., Lapillonne, H., Harris, D., Konopleva, M., Zhao, S., Estey, E., and Andreeff, M.
J. Clin. Invest. 108:851-859, 2001.
Treatment with low-dose interferon-alpha restores the balance between matrix metalloproteinase-9 and E-cadherin expression in human transitional cell carcinoma of the bladder
Slaton, J.W., Karashima, T., Perrotte, P., Inoue, K., Kim, S.J., Izawa, J., Kedar, D., McConkey, D.J., Millikan, R., Sweeney, P., Yoshikawa, C., Shuin, T., and Dinney, C.P.
Clin. Cancer Res., 7:2840-2853, 2001.
Transcription factor AP-2 alpha is preferentially cleaved by caspase 6 and degraded by proteasome during tumor necrosis factor alpha-induced apoptosis in breast cancer cells
Nyormoi, O., Wang, Z., Doan, D., Ruiz, M., McConkey, D., and Bar-Eli, M.
Mol. Cell. Biol., 21:4856-4867, 2001.
Calcium flux measurements in apoptosis
McConkey, D.J., and Nutt, L.K.
Methods Cell Biol., 66:229-246, 2001.
Endothelial cell apoptosis is inhibited by a soluble factor secreted by human colon cancer cells
Liu, W., Davis, D.W., Ramirez, K., McConkey, D.J., and Ellis, L.M.
Int. J. Cancer, 92:26-30, 2001.
NK-kB1 (p50) homodimers contribute to transcription of the bcl-2 oncogne
Kurland, J.F., Kodym, R., Story, M.D., Spurgers, K.B., McDonnell, T.J., and Meyn, R.E.
J. Biol. Chem., 276:45380-45386, 2001.
TRAIL (APO-2L) induces apoptosis in human prostate cancer cells that is inhabitable by Bcl-2
Munshi, A., Pappas, G., Honda, T., McDonnell, T.J., Younes, A., Li, Y., and Meyn, R.E.
Oncogene, 20:3757-3765, 2001.
A leukemic stem cell with intrinsic drug efflux capacity in acute myeloid leukemia
Wulf, G.G., Wang, R.Y., Kuehnle, I., Weidner, D., Marini, F., Brenner, M.K., Andreeff, M., and Goodell, M.A.
Blood, 98:1166-1173, 2001.
Autologous antileukemic immune response induced by chronic lymphocytic leukemia B cells expressing the CD40 ligand and interleukin 2 transgenes
Takahashi, S., Rousseau, R.F., Yotnda, P., Mei, Z., Dotti, G., Rill, D., Hurwitz, R., Marini, F., Andreeff, M., and Brenner, M.K.
Human Gene Therapy, 12:659-670, 2001.
Melanoma differentiation associated gene (mda7): a novel anti-tumor gene for cancer gene therapy
Mhashilkar, A.M., Schrock, R.D., Hindi, M., Liao, J., Sieger, K., Kourouma, F., Zou-Yang, H., Onishi, E., Takh, O., Vedvick, T.S., Stewart, L., Watson, G.J., Snary, D., Fisher, P.B., Ramesh, R., Roth, J.A., and Chada, S.
Mol. Med., 7:271-282, 2001.
Successful treatment of primary and disseminated human lung cancers by systemic delivery of tumor suppressor genes using an improved lipsome vector
Ramesh, R., Saeki, T., Templeton, N.S., Ji, L., Stephens, L.C., Ito, I., Wilson, D.R., Wu, Z., Branch, C.D., Minna, J.D., and Roth, J.A.
Mol. Ther., 3:337-350, 2001.
Correction of DiGeorge anomaly with EBV-transduced lymphoma by transplantation of organ cultured thymus and Epstein-Barr-specific cytotoxic T lymphocytes
Hong, R., Shen, V., Rooney, C.M., Smith, C., Comoli, P., Ho, D., and Zhang, L.
Clin. Immun., 98:54-61, 2001.
An Epstein-Barr virus deletion mutant associated with fatal lymphoproliferative disease unresponsible to therapy with virus-specific CTLs
Gottschalk, S., Ng, C., Perez, M., Smith, C.A., Sample, C., Brenner, M.K., Heslop, H.E., and Rooney, C.M.
Blood, 97:835-843, 2001.
Adenoviral gene transfer into dendritic cells efficiently amplifies the immune response to the 1mp2a-antigen: a potential treatment strategy for Epstein-Barr-virus-positive Hodgkin's lymphoma
Gahn, B., Lopez, F.S., Pirooz, A.D., Yvon, E., Gottschalk, S., Longnecker, R., Brenner, M.K., Heslop, H.E., Aguilar-Cordova, E., and Rooney, C.M.
Int. J. Cancer, 93:706-713, 2001.
Generation of autologous Epstein Barr Virus (EBV)-specific cytotoxic T cells (CTL) for adoptive immunothrapy in solid organ transplant recipients
Savoldo, B., Goss, J., Zu, L., Huls, M.H., Doster, S., Gee, A.P., Brenner, M.K., Heslop, H.E., and Rooney, C.M.
Transplantation, 72:1078-1086, 2001.
Accelerated degradation of cellular FLIP protein through the ubiquitin-proteasome pathway in p53-mediated apoptosis of human cancer cells
Fukazawa, T., Fujiwara, T., Kadowaki, Y., Shao, J., Waku, T., Itoshima, T., Takata, Y., Kagawa, S., Roth, J.A., Tschopp, J., and Tanaka, N.
Oncogene, 20:5225-5231, 2001
Anti-tumor activity and bystander effects of the TNF-related apoptosis-inducing ligand (TRAIL) gene
Kagawa, S., He, C., Gu, J., Koch, P., Rha, S-J, Roth, J.A., Curley, S.A., Stephens, L.C., and Fang, B.
Cancer Res., 61:3330-3338, 2001.
Adenovirus-mediated wild-type p53 gene expression radiosensitizes non-small cell lung cancer cells but not normal lung fibroblasts
Kawabe, S., Munshi, A., Zumstein, A., Wilson, D.R., Roth, J.A., and Meyn, R.E.
Int. J. Rad. Biol., 77:185-194, 2001.
Adenovirus-mediated antisense uPAR gene transfer reduces tumor cell invasion and metastasis in non-small cell lung cancer cell lines
Lakka, S.S., Ramesh, R., Rajan, M.K., Mohan, P.M., Ali-Osman, F., Roth, J.A., Yung, W.K.A., Kyritsis, A.P., and Rao, J.S.
Clin. Cancer Res., 7:1087-1093, 2001.
Phase-III intergroup trial of isotretinoin to prevent second primary tumors in stage I non-small-cell lung cancer
Lippman, S.M., Lee, J.J., Karp, D.D., Vokes, E.E., Benner, S.E., Goodman, G.E., Khuri, F.R., Kardinal, C.G., Winn, R.J., Williams, B., Perez, C., Lotan, R. Roth, J.A., and Hong, W.K.
J. Nat. Cancer Inst., 93:605-618, 2001.
Gene therapy: therapeutic approaches and implications
Mhashilkar, A., Chada, S., Roth, J.A., and Ramesh, R.
Biotech. Adv., 19:279-297, 2001.
Gene therapy: tumor suppressor gene replacement and oncogene supression
Roth, J.A., and Grammer S.F.
In: N. Lemoine and J. Abbruzzese (eds.)
The Cancer Handbook, London, MacMillan
in press, 2002.
p53 gene replacement for cancer: interactions with DNA damaging agents
Roth, J.A., Grammer, S.F., Swisher, S.G., Komaki, R., Nemunaitis, J., Merritt, J., and Meyn, R.E.
Acta Oncologica, 40:739-744, 2001.
Gene therapy approaches for the management of non-small cell lung cancer
Roth, J.A., Grammer, S.F., Swisher, S.G., Komaki, R., Nemunaitis, J., Merritt, J., and Meyn, R.E.
Sem. Oncol., 28:50-56, 2001.
Gene therapy approaches for the management of cancer
Roth, J.A.
2001 ASCO Spring Education Book, Baltimore, Lippincott Williams & Wilkins,
558-564, 2001.
Molecular determinants of cell death induction following adenoviral-mediated gene transfer of wild-type p53 in prostate cancer cells
Schumacher, G., Bruckheimer, E.M., Beham, A.W., Honda, T., Brisbay, S., Roth, J.A., Logothetis, C., and McDonnell, T.J.
Int. J. Cancer, 91:159-166, 2001.
Adenovirus-mediated bak gene transfer induces apoptosis in mesothelioma cell lines
Pataer, A., Smythe, W.R., Yu, R., Fang, B., McDonnell, T., Roth, J.A., and Swisher, S.G.
J. Thorac. Cardiovasc. Surg., 121:61-67, 2001.
Time-dose relationships in radiation-enhanced integration
Stevens, C.W, Puppi, M., and Cerniglia, G.J.
Int. J. Radiat. Biol., 77:841-846, 2001.
Grb2 downregulation leads to Akt inactivation in heregulin-stimulated and ErbB2-overexpressing breast cancer cells
Lim, S.-J., Lopez-Berenstein, G., Hung, M.-C., Lupu, R., and Tari, A.M.
Oncogne, 19:6271-6276, 2000.
'Mitotic drive' of expanded CTG repeats in myotonic dystrophy type 1 (DM1)
Khajavi, M., Tari, A.M., Patel, N.B., Tsuji, K., Siwak, D.R., Meistrich, M.L., Terry, N.H.A., and Ashizawa, T.
Human Mol. Genetics, 10:855-863, 2001.
Cationic liposome-mediated E1A gene transfer to human breast and ovarian cancer cells and its biologic effects: a phase I clinical trial
Hortobagyi, G.N., Ueno, N.T., Xia, W., Zhang, S., Wolf, J.K., Putnam, J.B., Weiden, P.L., Willey, J.S., Carey, M., Branham, D.L., Payne, J.Y., Tucker, S.D., Bartholomeusz, C., Kilbourn, R.G., De Jager, R.L., Sneige, N., Katz, R.L., Anklesaria, P., Ibrahim, N.K., Murray, J.L., Theriault, R.L., Valero, V., Gershenson, D.M., Bevers, M.W., Huang, L., Lopez-Verestein, G., and Hung, M.C.
J. Clin. Oncol., 19:3422-3433, 2001.
Introduction of mutant p53 into a wild-type p53-expressing glioma cell line confers sensitivity to Ad-p53-induced apoptosis
Cerrato, J.A., Yung, W.K.A., and Liu, T.J.
Neuro-Oncol., 3:113-122, 2001.
Survival and recurrence factors in adult medulloblastoma: The M. D. Anderson Cancer Center experience from 1978 to 1998
Kunschner, L.J., Kuttesch, J., Hess, K., and Yung, W.K.A.,
Neuro-Oncol., 14:167-173, 2001.
Inhibition of breast cancer growth in vivo by antiangiogenesis therapy with adenovirus-mediated antisense-VEGF
Im, S.A., Kim, J.S., Gomez-Manzano, C., Fueyo, J., Liu, T.J., Cho, M.S., Seong, C.M., Lee, S.N., Hong, Y.K., and Hung, W.K.A.
Br. J. Cancer, 84:1252-1257, 2001.
Coexpression of E2F-2 enhances the p53 anticancer effect in human glioma cells
Mitlianga, P. Kyritsis, A.P., Gomez-Manzano, C., Lemoine, M.G., Hu, M., Liu-T.-J., Yung, W.K.A., and Fueyo, J.
Int. J. Oncol., 18:343-347, 2001.
Tumor suppressor MMAC/PTEN inhibits cytokine-induced NFkB activation without interfering with the IkB degradation pathway
Koul, D., Yao, Y., Abbruzzese, J.L., Yung, W.K.A., and Reddy, S.A.G.
J. Biol. Chem, 276:11402-11408, 2001.

Archived 2000 Publications


Archived 1999 Publications


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