 2001
Publications
 |
Modulation
of nucleotide excision repair capacity by XPD polymorphisms
in lung cancer patients
Spitz,
M.R., Wu, X., Wang, Y., Wang, L.E., Shete, S., Amos, C.I.,
Guo, Z., Lei, L., Mohrenweiser, H., and Wei, Q.
Cancer Res., 61:1354-1357, 2001.
|
|
Age-associated
risk of cancer among individuals with N-acetyltransferase
2 (NAT2) mutations and mutations in DNA mismatch repair
genes
Frazier, M.L., O'Donnell, F.T., Kong, S., Gu, X., Campos,
I., Luthra, R., Lynch, P.M., and Amos, C.I.
Cancer Res., 61:1269-1271, 2001.
|
|
Genetic
linkage methods for quantitative traits
Amos, C.I., and de Andrade M.
Stat. Methods Med. Res., 10:3-25, 2001.
|
|
Cyclin
D1 polymorphisms and increased risk of colorectal cancer
at young age
Kong, S., Wei, Q., Amos, C.I., Lynch, P.M., Levin, B., Zong,
J., and Frazier, M.L.
J. Natl. Cancer Inst., 93:1106-1108, 2001. |
|
The
association of microsomal epoxide hydrolase polymorphisms
and lung cancer risk in African-Americans and Mexican-Americans
Wu, X., Gwyn, K., Amos, C.I., Makan, N., Hong, W.K., and
Spitz, M.R.
Carcinogenesis, 22:923-928, 2001. |
|
Cytokine-regulated
expression of survivin in myeloid leukemia
Carter, B.Z., Milella, M., Altieri, D.C., and Andreeff,
M.
Blood, 97:2784-2790, 2001. |
|
Expression
of apoptosis proteins in chronic myelogenous leukemia: associations
and significance
Ravandi, F., Kantarjian, H.M., Talpaz, M., O'Brien, S.,
Faderl, S., Giles, F.J., Thomas, D., Cortes, J., Andreeff,
M., Estrov, Z., Rios, M.B., and Albitar, M.
Cancer 91:1964-1972, 2001. |
|
BCR
gene expression blocks Bcr-Abl induced pathogenicity in
a mouse model
Lin, F., Monaco, G., Sun, T., Liu, J., Lin, H., Stephens,
C., Belmont, J., and Arlinghaus, R.B.
Oncogne, 20:1873-1881, 2001. |
|
Expression
of a truncated first exon BCR sequence in chronic myelogenous
leukemia cells blocks cell growth and induces cell death
Wang, Y., Liu, J., Wu, Y., Luo, W., Lin, S.H., Lin, H.,
Hawk, N., Sun, T., Guo, J.Q., Estrov, Z., Talpaz, M., Champlin,
R. and Arlinghaus R.B.
Cancer Res., 61:138-144, 2001. |
|
Preparation
and application of antibodies to phosphoamino acid sequences
Sun, T., Campbell, M., Gordon, W., and Arlinghaus, R.B.
Biopolymers, 60:61-75, 2001. |
|
Expression
of bcr-abl mRNA in individual chronic myelogenous leukemia
cells as determined by in situ amplification
Pachmann, K., Zhao, S., Schenk, T., Kantarjian, H., El-Naggar,
A.K., Siciliano, M.J., Guo, J.Q., Arlinghaus, R.B., and
Andreeff, M.
Br. J. Haematology, 112:749-759, 2001. |
|
p73
gene alterations and expression in primary oral and laryngeal
squamous carcinomas
El-Naggar, A.K., Lai, S., Clayman, G.L., Mims, B., Lippman,
S.M., Coombes, M., Luna, M.A., Lozano, G.
Carcinogenesis, 22:729-735, 2001. |
|
Epidermal
growth factor receptor-targeted therapy with C225 and cisplatin
in patients with head and neck cancer
Shin, D.M., Donato, N.J., Perez-Soler, R., Shin, H.J., Wu,
J.Y., Zhang, P., Lawhorn, K., Khuri, F.R., Glisson, B.S.,
Myers, J., Clayman, G., Pfister, D., Falcey, J., Waksal,
H., Mendelsohn J., and Hong, W.K.
Clin. Cancer Res., 7:1204-1213, 2001. |
|
SCCA1
expression in T-lymphocytes peripheral to cancer cells is
associated with the elevation of serum SCC antigen in squamous
cell carcinoma of the tongue
Yasumatsu, R., Nakashima, T., Azuma, K., Hirakawa, N., Kuratomi,
Y., Tomita, K., Cataltepe, S., Silverman, G.A., Clayman,
G.L., and Komiyama, S.
Cancer Lett., 167:205-213, 2001. |
|
Expression
of protease-activated receptor 1 in oral squamous cell carcinoma
Liu, Y., Gilcrease, M.Z., Henderson, Y., Yuan, X.H., Clayman,
G.L., and Chen, Z.
Cancer Lett., 169:173-180, 2001. |
|
All-trans-retinoic
acid enhances the effect of adenovirus-mediated wild-type
p53 gene transfer in head and neck squamous cell carcinoma
Nakashima, T., Sun, S.Y., Lotan, R., Fujiwara, T., Yasumatsu,
R., Komiyama, S., and Clayman, G.L.
Laryngoscope, 111:1459-1464, 2001. |
|
Connexin
26 enhances the bystander effect in HSVtk/GCV gene therapy
for human bladder cancer by adenovirus/PLL/DNA gene delivery
Tanaka, M., Frazier, G.C., De La Cerda, J., Cristiano, R.J.,
Liebert, M., and Grossman, H.B.
Gene Ther., 8:139-148, 2001. |
|
Augmenting
transgene expression from carcinoembryonic antigen (CEA)
promoter via a GAL4 gene regulatory system
Koch, P.E., Guo, Z.S., Kagawa, S., Gu, J., Roth, J.A., and
Fang, B.
Molecular Ther., 3:278-283, 2001. |
|
Deficiency
of caspase-3 in MCF7 cell blocks Bax-mediated nuclear fragmentation
but not cell death
Kagawa, S., Gu, J., Honda, T., McDonnell, T.J., Swisher,
S.G., Roth, J.A., and Fang, B.
Clin. Cancer Res., 7:1474-1480, 2001. |
|
Adenoviral-mediated
bax overexpression for the induction of therapeutic apoptosis
in prostate cancer
Li, X., Marani, M., Yu, J., He, Z., Fang, B., Roth, J.A.,
Denner, L., and Marcelli, M.
Cancer Res., 61:186-191, 2001.
|
|
Effects
of N-(4-hydroxyphenyl)retinamide on hTERT expression in
the bronchial epithelium of cigarette smokers
Soria, J.C., Moon, C., Wang, L. Hittelman, W.N., Jang, S.J.,
Sun, S.Y., Lee, J.J., Liu, D., Kurie, J.M., Morice, R.C.,
Lee, J.S., Hong, W.K., and Mao, L.
J. Natl. Cancer Inst., 93:1257-1265, 2001. |
|
Loss
of Fhit expression is a predictor of poor outcome in tongue
cancer
Lee, J.I., Soria, J.C., Hassan, K., Liu, D., Tang, X., El-Naggar,
A., Hong, W.K., and Mao, L.
Cancer Res., 61:837-841, 2001. |
|
Increased
reinoic acid responsiveness in lung carcinoma cells that
are nonresponsive despite the presence of endogenous retinoic
acid receptor (RAR) beta by expression of exogenous retinoid
receptors retinoid X receptor alpha, RAR alpha, and RAR
gamma
Wan, H., Hong, W.K., and Lotan, R.
Cancer Res., 61:556-564, 2001. |
|
Sensitivity
to DNA damage induced by benzo(a)pyrene diol epoxide and
risk of lung cancer: a case-control analysis
Li, D., Firozi, P.F., Wang, L.E., Bosken, C.H., Spitz, M.R.,
Hong, W.K., and Wei, Q.
Cancer Res., 61:1445-1450, 2001. |
|
Cyclooxygenase-2
overexpression is a marker of poor prognosis in stage I
non-small cell lung cancer
Khuri, F.R., Wu, H., Lee, J.J., Kemp, B.L., Lotan, R., Lippman,
S.M., Feng. L., Hong, W.K., and Xu, X.C.
Clin. Cancer Res., 7:861-867, 2001. |
|
Modulation
of proliferating cell nuclear antigen in the bronchial epithelium
of smokers
Khuri, F.R., Lee, J.S., Lippman, S.M., Lee, J.J., Kalapurakal,
S., Yu, R., Ro, J.Y., Morice, R.C., Hong, W.K., and Hittelman,
W.N.
Cancer Epidemiol. Biomarkers Prev., 10:311-318, 2001. |
|
Chromosome
polysomy and histological characteristics in oral premalignant
lesions
Kim, J., Shin, D.M., El-Naggar, A., Lee, J.S., Corrales,
C., Lippman, S.M., Hong, W.K., and Hittelman, W.N.
Cancer Epidemiol. Biomarkers Prev., 10:319-325, 2001. |
|
Polymorphisms
of methylene-tetrahydrofolate reductase and risk of lung
cancer: a case-control study
Shen, H., Spitz, M.R., Wang, L.E., Hong, W.K., and Wei,
Q.
Cancer Epidemiol. Biomarkers Prev., 10:397-401, 2001. |
|
Identification
of retinamides that are more potent than N-4(4-hydroxyphenyl)retinamide
in inhibiting growth and inducing apoptosis of human head
and neck and lung cancer cells
Sun, S.Y., Yue, P., Kelloff, G.J., Steele, V.E., Lippman,
S.M., Hong, W.K., and Lotan, R.
Cancer Epidemiol. Biomarkers Prev., 10:595-601, 2001. |
|
p53
protein accumulation and genomic instability in head and
neck multistep tumorigenesis
Shin, D.M., Charuruks, N., Lippman, S.M., Lee, J.J., Ro,
J.Y., Hong, W.K., and Hittelman, W.N.
Cancer Epidemiol. Biomarkers Prev., 10:603-609, 2001. |
|
In
vitro BPDE-induced DNA adducts in peripheral lymphocytes
as a risk factor for squamous cell carcinoma of the head
and neck
Li, D., Firozi, P.F.Chang, P., Wang, L.E., Xiong, P., Sturgis,
E.M., Eicher, S.A., Spitz, M.R., Hong, W.K., and Wei, Q.
Int. J. Cancer, 93:436-440, 2001. |
|
Clinical
significance of cyclin b1 protein expression in squamous
cell carcinoma of the tongue
Hassa, K.A., El-Naggar, A.K., Soria, J.C., Liu, D., Hong,
W.K., and Mao, L.
Clin. Cancer Res., 7:2458-2462, 2001. |
|
Synergistic
inhibition of human lung cancer cell growth by adenovirus-mediated
wild-type p53 gene transfer in combination with docetaxel
and radiation therapeutics in vitro and in vivo
Nishizaki, M., Meyn, R.E., Levy, L.B., Atkinson, E.N., White,
R.A., Roth, J.A., and Ji, L.
Clin. Cancer Res., 7:2887-2897, 2001. |
|
Interleukin
(IL)-12 and IL-12 gene transfer up-regulate Fas expression
in human osteosarcoma and breast cancer cells
Lafleur, E.A., Jia, S.-F., Worth, L.L., Zhou, Z., Owen-Schaub,
L.B., and Kleinerman, E.S.
Cancer Res., 61:4066-4071, 2001. |
|
E1A
sensitizes HER2/neu-overexpressing Ewing's sarcoma cells
to topoisomerase II-targeting anticancer drugs
Zhou, Z., Jia,S.-F., Hung, M.C., and Kleinerman, E.S.
Cancer Res., 61:3394-3398, 2001. |
|
Mylotarg
(gymtuzumab ozogamicin) therapy is associated with hepatic
venoocclusive disease in patients who have not received
stem cell transplantation
Giles, F.J., Kantajian, H.M., Kornblau, S.M., Thomas, D.A.,
Garcia-Manero, G., Waddelow, T.A., David, C.L., Phan, A.T.,
Colburn, D.R., Rashid, A., and Estey, E.H.
Cancer, 92:406-413, 2001. |
|
Preemptive
control of graft-versus-host disease in a murine allogeneic
transplant model using retrovirally transduced murine suicidal
lymphocytes
Kornblau, S.M., Stiouf, I., Snell, V., Przepiorka, D., Stevens,
L.C., Champlin, R., and Marini, 3rd, F.C.
Cancer Res., 61:3355-3360, 2001. |
|
Therapeutic
targeting of the MEK/MAPK signal transduction module in
acute myeloid leukemia
Milella, M., Kornblau, S.M., Estrov, Z., Carter, B.Z., Lapillonne,
H., Harris, D., Konopleva, M., Zhao, S., Estey, E., and
Andreeff, M.
J. Clin. Invest. 108:851-859, 2001. |
|
Treatment
with low-dose interferon-alpha restores the balance between
matrix metalloproteinase-9 and E-cadherin expression in
human transitional cell carcinoma of the bladder
Slaton, J.W., Karashima, T., Perrotte, P., Inoue, K., Kim,
S.J., Izawa, J., Kedar, D., McConkey, D.J., Millikan, R.,
Sweeney, P., Yoshikawa, C., Shuin, T., and Dinney, C.P.
Clin. Cancer Res., 7:2840-2853, 2001. |
|
Transcription
factor AP-2 alpha is preferentially cleaved by caspase 6
and degraded by proteasome during tumor necrosis factor
alpha-induced apoptosis in breast cancer cells
Nyormoi, O., Wang, Z., Doan, D., Ruiz, M., McConkey, D.,
and Bar-Eli, M.
Mol. Cell. Biol., 21:4856-4867, 2001. |
|
Calcium
flux measurements in apoptosis
McConkey, D.J., and Nutt, L.K.
Methods Cell Biol., 66:229-246, 2001. |
|
Endothelial
cell apoptosis is inhibited by a soluble factor secreted
by human colon cancer cells
Liu, W., Davis, D.W., Ramirez, K., McConkey, D.J., and Ellis,
L.M.
Int. J. Cancer, 92:26-30, 2001. |
|
NK-kB1
(p50) homodimers contribute to transcription of the bcl-2
oncogne
Kurland, J.F., Kodym, R., Story, M.D., Spurgers, K.B., McDonnell,
T.J., and Meyn, R.E.
J. Biol. Chem., 276:45380-45386, 2001. |
|
TRAIL
(APO-2L) induces apoptosis in human prostate cancer cells
that is inhabitable by Bcl-2
Munshi, A., Pappas, G., Honda, T., McDonnell, T.J., Younes,
A., Li, Y., and Meyn, R.E.
Oncogene, 20:3757-3765, 2001. |
|
A
leukemic stem cell with intrinsic drug efflux capacity in
acute myeloid leukemia
Wulf, G.G., Wang, R.Y., Kuehnle, I., Weidner, D., Marini,
F., Brenner, M.K., Andreeff, M., and Goodell, M.A.
Blood, 98:1166-1173, 2001. |
|
Autologous
antileukemic immune response induced by chronic lymphocytic
leukemia B cells expressing the CD40 ligand and interleukin
2 transgenes
Takahashi, S., Rousseau, R.F., Yotnda, P., Mei, Z., Dotti,
G., Rill, D., Hurwitz, R., Marini, F., Andreeff, M., and
Brenner, M.K.
Human Gene Therapy, 12:659-670, 2001. |
|
Melanoma
differentiation associated gene (mda7): a novel anti-tumor
gene for cancer gene therapy
Mhashilkar, A.M., Schrock, R.D., Hindi, M., Liao, J., Sieger,
K., Kourouma, F., Zou-Yang, H., Onishi, E., Takh, O., Vedvick,
T.S., Stewart, L., Watson, G.J., Snary, D., Fisher, P.B.,
Ramesh, R., Roth, J.A., and Chada, S.
Mol. Med., 7:271-282, 2001. |
|
Successful
treatment of primary and disseminated human lung cancers
by systemic delivery of tumor suppressor genes using an
improved lipsome vector
Ramesh, R., Saeki, T., Templeton, N.S., Ji, L., Stephens,
L.C., Ito, I., Wilson, D.R., Wu, Z., Branch, C.D., Minna,
J.D., and Roth, J.A.
Mol. Ther., 3:337-350, 2001. |
|
Correction
of DiGeorge anomaly with EBV-transduced lymphoma by transplantation
of organ cultured thymus and Epstein-Barr-specific cytotoxic
T lymphocytes
Hong, R., Shen, V., Rooney, C.M., Smith, C., Comoli, P.,
Ho, D., and Zhang, L.
Clin. Immun., 98:54-61, 2001. |
|
An
Epstein-Barr virus deletion mutant associated with fatal
lymphoproliferative disease unresponsible to therapy with
virus-specific CTLs
Gottschalk, S., Ng, C., Perez, M., Smith, C.A., Sample,
C., Brenner, M.K., Heslop, H.E., and Rooney, C.M.
Blood, 97:835-843, 2001. |
|
Adenoviral
gene transfer into dendritic cells efficiently amplifies
the immune response to the 1mp2a-antigen: a potential treatment
strategy for Epstein-Barr-virus-positive Hodgkin's lymphoma
Gahn, B., Lopez, F.S., Pirooz, A.D., Yvon, E., Gottschalk,
S., Longnecker, R., Brenner, M.K., Heslop, H.E., Aguilar-Cordova,
E., and Rooney, C.M.
Int. J. Cancer, 93:706-713, 2001. |
|
Generation
of autologous Epstein Barr Virus (EBV)-specific cytotoxic
T cells (CTL) for adoptive immunothrapy in solid organ transplant
recipients
Savoldo, B., Goss, J., Zu, L., Huls, M.H., Doster, S., Gee,
A.P., Brenner, M.K., Heslop, H.E., and Rooney, C.M.
Transplantation, 72:1078-1086, 2001. |
|
Accelerated
degradation of cellular FLIP protein through the ubiquitin-proteasome
pathway in p53-mediated apoptosis of human cancer cells
Fukazawa, T., Fujiwara, T., Kadowaki, Y., Shao, J., Waku,
T., Itoshima, T., Takata, Y., Kagawa, S., Roth, J.A., Tschopp,
J., and Tanaka, N.
Oncogene, 20:5225-5231, 2001 |
|
Anti-tumor
activity and bystander effects of the TNF-related apoptosis-inducing
ligand (TRAIL) gene
Kagawa, S., He, C., Gu, J., Koch, P., Rha, S-J, Roth, J.A.,
Curley, S.A., Stephens, L.C., and Fang, B.
Cancer Res., 61:3330-3338, 2001. |
|
Adenovirus-mediated
wild-type p53 gene expression radiosensitizes non-small
cell lung cancer cells but not normal lung fibroblasts
Kawabe, S., Munshi, A., Zumstein, A., Wilson, D.R., Roth,
J.A., and Meyn, R.E.
Int. J. Rad. Biol., 77:185-194, 2001. |
|
Adenovirus-mediated
antisense uPAR gene transfer reduces tumor cell invasion
and metastasis in non-small cell lung cancer cell lines
Lakka, S.S., Ramesh, R., Rajan, M.K., Mohan, P.M., Ali-Osman,
F., Roth, J.A., Yung, W.K.A., Kyritsis, A.P., and Rao, J.S.
Clin. Cancer Res., 7:1087-1093, 2001. |
|
Phase-III
intergroup trial of isotretinoin to prevent second primary
tumors in stage I non-small-cell lung cancer
Lippman, S.M., Lee, J.J., Karp, D.D., Vokes, E.E., Benner,
S.E., Goodman, G.E., Khuri, F.R., Kardinal, C.G., Winn,
R.J., Williams, B., Perez, C., Lotan, R. Roth, J.A., and
Hong, W.K.
J. Nat. Cancer Inst., 93:605-618, 2001. |
|
Gene
therapy: therapeutic approaches and implications
Mhashilkar, A., Chada, S., Roth, J.A., and Ramesh, R.
Biotech. Adv., 19:279-297, 2001. |
|
Gene
therapy: tumor suppressor gene replacement and oncogene
supression
Roth, J.A., and Grammer S.F.
In: N. Lemoine and J. Abbruzzese (eds.)
The Cancer Handbook, London, MacMillan
in press, 2002. |
|
p53
gene replacement for cancer: interactions with DNA damaging
agents
Roth, J.A., Grammer, S.F., Swisher, S.G., Komaki, R., Nemunaitis,
J., Merritt, J., and Meyn, R.E.
Acta Oncologica, 40:739-744, 2001. |
|
Gene
therapy approaches for the management of non-small cell
lung cancer
Roth, J.A., Grammer, S.F., Swisher, S.G., Komaki, R., Nemunaitis,
J., Merritt, J., and Meyn, R.E.
Sem. Oncol., 28:50-56, 2001. |
|
Gene
therapy approaches for the management of cancer
Roth, J.A.
2001 ASCO Spring Education Book, Baltimore, Lippincott Williams
& Wilkins,
558-564, 2001. |
|
Molecular
determinants of cell death induction following adenoviral-mediated
gene transfer of wild-type p53 in prostate cancer cells
Schumacher, G., Bruckheimer, E.M., Beham, A.W., Honda, T.,
Brisbay, S., Roth, J.A., Logothetis, C., and McDonnell,
T.J.
Int. J. Cancer, 91:159-166, 2001. |
|
Adenovirus-mediated
bak gene transfer induces apoptosis in mesothelioma cell
lines
Pataer, A., Smythe, W.R., Yu, R., Fang, B., McDonnell, T.,
Roth, J.A., and Swisher, S.G.
J. Thorac. Cardiovasc. Surg., 121:61-67, 2001. |
|
Time-dose
relationships in radiation-enhanced integration
Stevens, C.W, Puppi, M., and Cerniglia, G.J.
Int. J. Radiat. Biol., 77:841-846, 2001. |
|
Grb2
downregulation leads to Akt inactivation in heregulin-stimulated
and ErbB2-overexpressing breast cancer cells
Lim, S.-J., Lopez-Berenstein, G., Hung, M.-C., Lupu, R.,
and Tari, A.M.
Oncogne, 19:6271-6276, 2000. |
|
'Mitotic
drive' of expanded CTG repeats in myotonic dystrophy type
1 (DM1)
Khajavi, M., Tari, A.M., Patel, N.B., Tsuji, K., Siwak,
D.R., Meistrich, M.L., Terry, N.H.A., and Ashizawa, T.
Human Mol. Genetics, 10:855-863, 2001. |
|
Cationic
liposome-mediated E1A gene transfer to human breast and
ovarian cancer cells and its biologic effects: a phase I
clinical trial
Hortobagyi, G.N., Ueno, N.T., Xia, W., Zhang, S., Wolf,
J.K., Putnam, J.B., Weiden, P.L., Willey, J.S., Carey, M.,
Branham, D.L., Payne, J.Y., Tucker, S.D., Bartholomeusz,
C., Kilbourn, R.G., De Jager, R.L., Sneige, N., Katz, R.L.,
Anklesaria, P., Ibrahim, N.K., Murray, J.L., Theriault,
R.L., Valero, V., Gershenson, D.M., Bevers, M.W., Huang,
L., Lopez-Verestein, G., and Hung, M.C.
J. Clin. Oncol., 19:3422-3433, 2001. |
|
Introduction
of mutant p53 into a wild-type p53-expressing glioma cell
line confers sensitivity to Ad-p53-induced apoptosis
Cerrato, J.A., Yung, W.K.A., and Liu, T.J.
Neuro-Oncol., 3:113-122, 2001. |
|
Survival
and recurrence factors in adult medulloblastoma: The M.
D. Anderson Cancer Center experience from 1978 to 1998
Kunschner, L.J., Kuttesch, J., Hess, K., and Yung, W.K.A.,
Neuro-Oncol., 14:167-173, 2001. |
|
Inhibition
of breast cancer growth in vivo by antiangiogenesis therapy
with adenovirus-mediated antisense-VEGF
Im, S.A., Kim, J.S., Gomez-Manzano, C., Fueyo, J., Liu,
T.J., Cho, M.S., Seong, C.M., Lee, S.N., Hong, Y.K., and
Hung, W.K.A.
Br. J. Cancer, 84:1252-1257, 2001. |
|
Coexpression
of E2F-2 enhances the p53 anticancer effect in human glioma
cells
Mitlianga, P. Kyritsis, A.P., Gomez-Manzano, C., Lemoine,
M.G., Hu, M., Liu-T.-J., Yung, W.K.A., and Fueyo, J.
Int. J. Oncol., 18:343-347, 2001. |
|
Tumor
suppressor MMAC/PTEN inhibits cytokine-induced NFkB activation
without interfering with the IkB degradation pathway
Koul, D., Yao, Y., Abbruzzese, J.L., Yung, W.K.A., and Reddy,
S.A.G.
J. Biol. Chem, 276:11402-11408, 2001. |
Archived
2000 Publications
Archived
1999 Publications
Return
to Top
|
